组织工程与重建外科杂志2024，Vol.20Issue(5)：579-583,5.DOI:10.3969/j.issn.1673-0364.2024.05.014
丛状神经纤维瘤的复发影响因素
Factors affecting recurrence of plexiform neurofibromas
摘要
Abstract
Plexiform neurofibromas (pNF) is an autosomal dominant condition of the nervous system and surgical treatment is the main treatment for pNF.However,it is difficult to remove completely,and postoperative recurrence is common.Based on extensive investigation of domestic and foreign cohort research,the existing factors affecting recurrence of pNF were summarized and analyzed.The recurrence of pNF is mainly related to the location of the primary tumor,the extent of surgical resection,and the age of the patients.Other factors such as tumor growth pattern,depth of invasion,nerve origin,preoperative tumor size,and degree of tumor pain are possible affecting factors for recurrence.At present,there is still a lack of preoperative comprehensive evaluation criteria based on multiple factors,and it is more necessary to rely on the experience of clinicians for surgical judgment.There are some problems in previous studies,such as small sample size,imprecise classification of patients,the factors studied were relatively single,and lack of comprehensive quantitative processing.New clinical cohort studies are needed to provide further evidence support and prognostic evaluation criteria.关键词
丛状神经纤维瘤/复发/队列研究Key words
Plexiform neurofibromas/Recurrence/Cohort study分类
医药卫生引用本文复制引用
谭好,朱子骋,苏佳琦,黄健峰,曾丹奕,王智超..丛状神经纤维瘤的复发影响因素[J].组织工程与重建外科杂志,2024,20(5):579-583,5.基金项目
国家自然科学基金资助项目(82472579,82102344,82172228,82202470) （82472579,82102344,82172228,82202470）
上海市整形外科重点研究中心(2023ZZ02023) （2023ZZ02023）
上海市科学技术委员会临床医学研究中心项目(22MC1940300) （22MC1940300）
上海交通大学医学院附属第九人民医院生物样本库项目(YBKA202204) （YBKA202204）
上海交通大学医学院创新训练项目(1723Y035). （1723Y035）
