Diet restriction and exercise alleviate cognitive reduction of high fat diet (HFD)-induced obese mice by rescuing inflammation-mediated compromised insulin signaling pathway through activating AMPK/SIRT1 signal pathway and suppressing TLR4 signal pathway
Hu Zhang Ye Zhang Jiling Liang Jiahang Li Miao He Xin Liu Jielun Huang Minghui Wang Jingjing Fan Ning Chen
Diet restriction and exercise alleviate cognitive reduction of high fat diet (HFD)-induced obese mice by rescuing inflammation-mediated compromised insulin signaling pathway through activating AMPK/SIRT1 signal pathway and suppressing TLR4 signal pathway
摘要
关键词
Cognitive capacity/Exercise intervention/Diet restriction/Inflammation/Insulin signaling pathway/Obesity分类
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Hu Zhang,Ye Zhang,Jiling Liang,Jiahang Li,Miao He,Xin Liu,Jielun Huang,Minghui Wang,Jingjing Fan,Ning Chen..Diet restriction and exercise alleviate cognitive reduction of high fat diet (HFD)-induced obese mice by rescuing inflammation-mediated compromised insulin signaling pathway through activating AMPK/SIRT1 signal pathway and suppressing TLR4 signal pathway[J].Food Science and Human Wellness,2024,13(6):P.3171-3180,10.基金项目
supported by the National Natural Science Foundation of China(32471186,31771318) （32471186,31771318）
the 14th Five-Year-Plan Advantageous and Characteristic Disciplines(Groups)of Colleges and Universities in Hubei Province for Exercise and Brain Science from Hubei Provincial Department of Education,and the Leading Talent Program Foundation from Wuhan Sports University to Ning Chen （Groups）
and the National Natural Science Foundation of China(81701391) （81701391）
the Natural Science Foundation of Hubei Province(2023AFB700) （2023AFB700）
Key Project of Scientific Research of Education Department of Hubei Province(D20234101) （D20234101）
Young and Middle aged Scientific Research Team Project of Wuhan Sports University(21KT08)to Jingjing Fan. （21KT08）
