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Suppression of NFATc1 through NF-kB/PI3K signaling pathway by Oleandrin to inhibit osteoclastogenesis and bone resorption

Zhikun Li Kai Chen Qifeng Yu Yifan Li Shichao Tong Ruijun Xu Ruixi Hu Yi Zhang Wei Xu

Engineered Regeneration2024，Vol.5Issue(3)：P.342-349,8.

Engineered Regeneration2024，Vol.5Issue(3)：P.342-349,8.DOI:10.1016/j.engreg.2024.01.005

Suppression of NFATc1 through NF-kB/PI3K signaling pathway by Oleandrin to inhibit osteoclastogenesis and bone resorption

Zhikun Li ¹Kai Chen ²Qifeng Yu ¹Yifan Li ¹Shichao Tong ¹Ruijun Xu ¹Ruixi Hu ¹Yi Zhang ³Wei Xu¹

作者信息

1. Department of Orthopedic,TongRen Hospital,School of Medicine,Shanghai Jiao Tong University,1111 Xianxia Road,Shanghai 200336,People’s Republic of China
2. Department of Orthopaedic,Naval Medical University First Affiliated Hospital,200433,168 Changhai Road,Yangpu District,Shanghai,People’s Republic of China
3. Department of Traditional Chinese Medicine,TongRen Hospital,School of Medicine,Shanghai Jiao Tong University,1111 Xianxia Road,Shanghai 200336,People’s Republic of China
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摘要

关键词

Osteoclastogenesis/Osteolysis/NF-κB/PI3K/Oleandrin/NFATc1

分类

医药卫生

引用本文复制引用

Zhikun Li,Kai Chen,Qifeng Yu,Yifan Li,Shichao Tong,Ruijun Xu,Ruixi Hu,Yi Zhang,Wei Xu..Suppression of NFATc1 through NF-kB/PI3K signaling pathway by Oleandrin to inhibit osteoclastogenesis and bone resorption[J].Engineered Regeneration,2024,5(3):P.342-349,8.

基金项目

National Natural Science Foundation of China(82272165) （82272165）

Shanghai Municipal Commission of Health and Family Planning’s Science and Research Fund(202040141) （202040141）

Shanghai Municipality Science and Technology Commission(20ZR1451800,22ZR1457200) （20ZR1451800,22ZR1457200）

Shanghai Municipal Health Commission(2022YQ006) （2022YQ006）

Shanghai Tongren Hospital(TRKYRC-xx202203). （TRKYRC-xx202203）

Engineered Regeneration

ISSN：2666-1381

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