波谱学杂志2024，Vol.41Issue(4)：382-392,11.DOI:10.11938/cjmr20243101
dDNP溶融系统的自动化设计与研究
Design and Research of the dDNP Automated Dissolution System
摘要
Abstract
Dissolution dynamic nuclear polarization(dDNP)involves polarizing the sample under microwave irradiation at a low-temperature and strong-magnetic field,dissolving it by solvent of high-temperature and high-pressure,then injecting it rapidly into an NMR/MRI for detection.The dissolution system serves as a pivotal component in the dissolving and injecting process,with its performance directly affecting the melting and transfer efficiency and the high polarization retention.We present an automated dissolution system using a dual-loop proportional-integral-derivative(PID)control algorithm that can reach the target pressure of～1.7 MPa after 9 min and control the internal pressure within 1.5%.The system can dissolve a solid sample of-271℃in the self-developed 5 T dDNP polarizer and transfer it to the 7 T NMR system at a distance of 11.2 m for detection in 4 s,yielding a 9050-fold enhancement of 13C NMR signal of sodium[1-13C]-pyruvate at the solvated state.In summary,this work developed an automated dissolution system that simplifies the operation steps,ensures detection consistency,and improves experimental safety.关键词
溶融动态核极化/双闭环PID控制算法/溶融系统/高温高压Key words
dissolution dynamic nuclear polarization/double-loop PID control algorithm/dissolution system/high temperature and high pressure分类
数理科学引用本文复制引用
曾祥政,陈俊飞,黄重阳,皮海亚,曹丽,黄臻,郭文龙,冯继文,刘朝阳..dDNP溶融系统的自动化设计与研究[J].波谱学杂志,2024,41(4):382-392,11.基金项目
国家自然科学基金重大科研仪器研制项目(22327901),国家重点研发计划项目(2022YFF0707001),国家自然科学基金青年项目(22204168,12205352),曙光计划项目(2022010801020130),中国科学院B类先导专项(XDB0540301). （22327901）
