高等学校化学学报2024，Vol.45Issue(12)：22-30,9.DOI:10.7503/cjcu20240322
诺氟沙星印迹电化学传感器的制备及检测性能
Preparation and Detection Performance of Norfloxacin Imprinted Electrochemical Sensor
摘要
Abstract
Aiming at the trace detection of norfloxacin(NOR),an electrochemical sensor with high sensitivity and selectivity for NOR was constructed by taking advantage of electrochemical analysis and the selectivity of molecularly imprinted polymers,and taking metal-organic framework(MOF)doped with highly conductive materials as a mimetic enzyme.Among them,the molecularly imprinted polymer membrane was obtained by electropolymerization with NOR as a template and o-phenylenediamine as a functional monomer.The results show that the linear range of the sensor is 1.0×10‒7-1.0×10‒5mol/L,the linear regression equation is I=-30.682-37.505lgc,the correlation coefficient is 0.987,and the detection limit reaches 3.2×10‒9 mol/L.In the detection of actual samples,the sensor shows high sensitivity(relative standard deviation is 3.0%)and high accuracy(recovery rate is 96.6%—102.3%),which shows that it has application potential in drug dosage detection and environmental monitoring.关键词
电化学传感器/金属有机框架/分子印迹聚合物/诺氟沙星Key words
Electrochemical sensor/Metal-organic framework/Molecular imprinting/Norfloxacin分类
化学化工引用本文复制引用
李嘉慧,张剑,严龙,丰芸,章家立,刘永鑫,杨绍明..诺氟沙星印迹电化学传感器的制备及检测性能[J].高等学校化学学报,2024,45(12):22-30,9.基金项目
国家自然科学基金(批准号:52361014)资助.Supported by the National Natural Science Foundation of China(No.52361014). （批准号:52361014）
