河北医学2024，Vol.30Issue(11)：1853-1858,6.DOI:10.3969/j.issn.1006-6233.2024.11.018
血清肌酸激酶同工酶联合血乳酸预测多发伤患者短期预后的价值
Value of Serum Creatine Kinase Isoenzyme Combined with Blood Lactic Acid on Predicting Short-Term Prognosis in Patients with Multiple Trauma
摘要
Abstract
Objective:To analyze the value of serum creatine kinase isoenzyme(CK-MB)combined with blood lactic acid on the prediction of short-term prognosis in patients with multiple trauma.Methods:Totally 119 patients with multiple trauma in the hospital were collected from January 2020 to December 2023 as the study subjects,and were divided into survival group(n=99)and death group(n=20)by means of 28-day prognosis status.Serum CK-MB and blood lactic acid levels of all subjects were measured after admis-sion.The prediction model with CK-MB and blood lactic acid as variables was constructed by binary Logistic regression analysis.Receiver operating characteristic curve(ROC)was performed to analyze the predictive value of serum CK-MB and blood lactic acid on short-term prognosis of patients.Results:The levels of ser-um CK-MB and blood lactic acid in the death group were higher than those in the survival group(P<0.05).Logistic regression analysis indicated that CK-MB and blood lactic acid were independent predictors of short-term prognosis in patients with multiple trauma,and the prediction model was logit(P)=-6.789+0.188×CK-MB+0.234×blood lactic acid.ROC curve analysis showed that the area under the curve(AUC),sen-sitivity and specificity of serum CK-MB combined with blood lactic acid in predicting the short-term prognosis were 0.997,100.00%and 98.99%,which were better than each indicator alone(P<0.05).Conclusion:Serum CK-MB and blood lactic acid are closely related to the short-term prognosis in patients with multiple trauma.Early detection of CK-MB and blood lactic acid levels has certain predictive value on the short-term prognosis of patients with multiple trauma,and the combined prediction of the two indicators is more effective.关键词
多发伤/短期预后/血清肌酸激酶同工酶/血乳酸/预测价值Key words
Multiple trauma/Short-term prognosis/Serum creatine kinase isoenzyme/Blood lactic acid/Predictive value引用本文复制引用
凌霄,朱冠能,吴思苇,黄淑晴,吴文辉..血清肌酸激酶同工酶联合血乳酸预测多发伤患者短期预后的价值[J].河北医学,2024,30(11):1853-1858,6.基金项目
2020年度安徽省自然科学基金项目,(编号:2008085QH406) （编号:2008085QH406）
