解剖学杂志2024，Vol.47Issue(5)：375-379,5.DOI:10.3969/j.issn.1001-1633.2024.05.001
少突胶质细胞异常在抑郁症病理机制中的作用
Role of oligodendroglial abnormalities in the pathogenesis of depression
摘要
Abstract
Depression is a mental illness primarily characterized by persistent emotional lowness,which can escalate to suicidal behaviors in severe cases.The underlying mechanisms of depression are intricate and multifaceted.Recent research has solidified the role of oligodendroglia in the pathogenesis of depression,influenced by both genetic and environmental factors.Drawing upon clinical data and the established link between oligodendrocyte abnormalities and depression,this article briefly summarizes the progress made in experimental studies regarding the role of oligodendroglial cells and myelin sheath abnormalities in the pathological mechanisms of depression,with the goal of offering fresh perspectives for the treatment of patients with depression.关键词
抑郁症/少突胶质细胞/髓鞘Key words
depression/oligodendrocyte/myelin sheath分类
医药卫生引用本文复制引用
王玉鑫,肖岚..少突胶质细胞异常在抑郁症病理机制中的作用[J].解剖学杂志,2024,47(5):375-379,5.基金项目
国家自然科学基金(82301703) （82301703）
西藏自治区自然科学基金(XZ202401ZR0011) （XZ202401ZR0011）
