中国当代医药2024，Vol.31Issue(33)：79-82,4.
派特灵治疗人乳头瘤病毒感染阴道壁低级别病变的远期效果
Long term efficacy analysis of Paiteling in the treatment of low-grade le-sions of the vaginal wall caused by human papillomavirus infection
摘要
Abstract
Objective To analyze the long-term effects of using Pectin to treat low-grade lesions of the vaginal wall caused by human papillomavirus(HPV)infection.Methods A total of sixty patients with HPV positive and low-grade vaginal wall lesions were selected as the study subjects from January 2020 to December 2021 admitted to the Jiangxi Maternal and Child Health Hospital.They were divided into a control group(30 cases)and a study group(30 cases)according to random number table method.The control group received the Baofukang suppository method,while the study group received the Paitelin treatment method.Followed up for 2 years,the HPV seroconversion,vaginal intraepithelial neoplasia(VAINI)seroconver-sion,liquid based thin-layer cell test(TCT)outcome,and adverse reactions between the two groups were compared.Results The HPV conversion rate of patients in the study group at 24 months of follow-up was higher than that in the same group at 6 months of follow-up,and the HPV conversion rate of patients in the control group at 18 and 24 months of follow-up was higher than that in the same group at 6 months of follow-up and the HPV conversion rate of patients in the study group at 6,12,18,and 24 months of follow-up was higher than that of the control group,and the difference was statistically significant(P＜0.05).The VAINI conversion rate of the two groups of patients at 24 months of follow-up was higher than that of the same group at 6 months of follow-up and the VAINI conversion rate of the study group patients at 6,12,18 and 24 months of follow-up was higher than that of the control group,and the difference was statistically significant(P＜0.05).The TCT outcome rate of patients in the study group at 24 months of follow-up was higher than that of patients in the same group at 6,12,and 18 months of follow-up and the TCT outcome rate of patients in the control group at 24 months of follow-up was higher than that of patients in the same group at 6 and 12 months of follow-up and the TCT outcome rate of patients in the study group at 6,12,18,and 24 months of follow-up was higher than that of the control group,and the difference was statis-tically significant(P＜0.05).There was no statistically significant difference in the total incidence of adverse reactions be-tween the two groups(P＞0.05).Conclusion Compared with Baofukang suppositories,Paiteling can improve the HPV con-version rate/vaginal wall conversion rate and TCT conversion rate in the treatment of low-grade lesions caused by HPV in-fection,without increasing adverse reactions.关键词
人乳头瘤病毒/派特灵/疗效/不良反应Key words
Human papillomavirus/Pateling/Therapeutic effect/Adverse reactions分类
医药卫生引用本文复制引用
雷丽华,李风英,吴忧,王凤,王艺,冯云华..派特灵治疗人乳头瘤病毒感染阴道壁低级别病变的远期效果[J].中国当代医药,2024,31(33):79-82,4.基金项目
江西省卫生健康委科技计划项目(202410948). （202410948）
