HBV母婴零传播——从争议到共识OA北大核心CSTPCD

Mother-to-child transmission is the major route of transmission for hepatitis B virus(HBV),and prevention of the mother-to-child transmission of HBV is the key link in the prevention and control of hepatitis B and one of the five essential core strategies for achieving the global elimination of hepatitis B by 2030.Combined immunization for neonates born to HBV-infected mothers and maternal antiviral intervention during pregnancy are important measures for blocking mother-to-child transmission,and thereby,the implementation of the comprehensive strategy of combined immunization and maternal antiviral intervention will help to accelerate the process of eliminating mother-to-child transmission.Chinese scholars have put forward the concept of"zero mother-to-child transmission of hepatitis B"and launched"Shield Program"in China,aiming to promote the implementation of the preventive strategy for mother-to-child transmission and lay a solid foundation for eliminating viral hepatitis in China.The Shield Program has provided detailed implementation strategies,successful practice experience,and reliable data for blocking the mother-to-child transmission of hepatitis B,fostering the consensus on the zero mother-to-child transmission of HBV in the academic community,and it also has an important reference value for eliminating the mother-to-child transmission of HBV in China and globally.