临床肝胆病杂志2024，Vol.40Issue(11)：2141-2144,4.DOI:10.12449/JCH241102
阻断HBV母婴传播:热点与难点
Hotspots and challenges in blocking the mother-to-child transmission of hepatitis B virus
摘要
Abstract
Chronic hepatitis B virus(HBV)infection remains a major public health challenge in China,affecting over 70 million people and posing great challenges to the prevention and control of the disease.At present,both the government and sectors of the society are making efforts to achieve the goal of eliminating viral hepatitis as a public health threat by 2030.Mother-to-child transmission is the main route of transmission of HBV,and therefore,blocking the mother-to-child transmission of HBV is the key link in eliminating viral hepatitis.At present,several critical issues still remain unresolved,including the long-term safety of tenofovir alafenamide fumarate during pregnancy,the safety of antiviral therapy in early pregnancy,the effectiveness of immunoglobulin-free strategy,and the risk of HBV transmission through germ cells.Addressing these challenges is important for promoting the blocking of the mother-to-child transmission of HBV and accelerating the progress toward the 2030 goals.关键词
乙型肝炎病毒/传染性疾病传播,垂直/孕妇Key words
Hepatitis B Virus/Infectious Disease Transmission,Vertical/Pregnant Women引用本文复制引用
尹雪如,洪睿轩,刘志华,侯金林..阻断HBV母婴传播:热点与难点[J].临床肝胆病杂志,2024,40(11):2141-2144,4.基金项目
广州市科技基础与应用基础研究专题(2023A04J2299) Science and Technology Projects in Guangzhou(2023A04J2299) （2023A04J2299）
