求同存异,兼容并济——从国内外慢加急性肝衰竭定义的演变历程统一共识OA北大核心CSTPCD
Unified consensus and evolution of the definition of acute-on-chronic liver failure:Seeking common ground while reserving differences
在慢加急性肝衰竭(ACLF)这一概念被提出的近30年来,随着对其发病机制、诊断标准、治疗措施等各个方面研究的不断深入,来自全球范围内的相关诊疗共识指南也在不断更新,但ACLF的定义始终未得到统一,定义的不同必然会阻碍诸多治疗手段、预后评分、诊疗意见的推广应用.近年来,肝病学专家们不断提出了统一ACLF定义的方式方法,求同存异,取长补短,最终力求使ACLF的定义趋于一致.
The concept of acute-on-chronic liver failure(ACLF)has been introduced for nearly 30 years,and with extensive research on its pathogenesis,diagnostic criteria,and treatment strategies,related consensus statements and guidelines have been constantly updated in China and globally;however,there is still a lack of a unified definition of ACLF,and such differences in definition may inevitably hinder the application and implementation of various treatment methods,prognostic scoring systems,and clinical recommendations.In recent years,hepatology experts have continuously proposed methods to unify the definition of ACLF,seeking common ground while reserving differences and drawing on the strengths of various definitions,in order to achieve a more unified definition of ACLF.
徐曼曼;陈煜
首都医科大学附属北京佑安医院肝病中心四科,北京 100069
慢加急性肝功能衰竭定义演变
Acute-on-Chronic Liver FailureDefinitionEvolution
《临床肝胆病杂志》 2024 (011)
2173-2176 / 4
北京市高层次公共卫生技术人才建设基金资助项目(学科带头人-01-12);北京市医院管理中心"登峰"计划专项经费资助项目(DFL20221501) Construction Project of High-level Technology Talents in Public Health(Discipline Leader-01-12);Beijing Hospitals Authority's Ascent Plan(DFL20221501)
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