强激光与粒子束2024,Vol.36Issue(12):150-156,7.DOI:10.11884/HPLPB202436.240095
基于EBT3胶片开展电子FLASH放疗剂量测量研究
Study of electron FLASH radiotherapy dose measurement based on EBT3 film
摘要
Abstract
FLASH radiotherapy delivers the entire dose to the target area within milliseconds using ultra-high dose rates,rendering existing online dosimeters essentially ineffective.Currently,radiation-sensitive films are commonly employed for dose measurement.Utilizing an electron accelerator developed by the Institute of Applied Electronics of CAEP,an electron FLASH radiotherapy platform was established to investigate the dose rate range and dose distribution using the EBT3 film's rapid readout method.Experimental results indicate that the rapid readout method of EBT3 films is applicable for dose measurement in electron FLASH radiotherapy,with dose rates ranging from 240 Gy/s to 290 Gy/s at a source-to-skin distance of 100 cm and a depth of 1 cm.Fluctuations in the average energy of the electron beam reaching the surface of the phantom result in dose fluctuations of approximately±5%in the target area.The surface dose distribution meets the requirements of flatness within±5%and symmetry within±3%.关键词
放射治疗/超高剂量率/EBT3胶片/剂量测量/电子FLASH放疗平台Key words
radiation therapy/ultra-high dose rate/Gafchromic EBT3/dosimetry/electron FLASH radiotherapy platform分类
医药卫生引用本文复制引用
王诗岚,羊奕伟,程德琪,唐镭迅,吴岱..基于EBT3胶片开展电子FLASH放疗剂量测量研究[J].强激光与粒子束,2024,36(12):150-156,7.基金项目
国家自然科学基金项目(12375318) (12375318)