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基于EBT3胶片开展电子FLASH放疗剂量测量研究

王诗岚 羊奕伟 程德琪 唐镭迅 吴岱

强激光与粒子束2024,Vol.36Issue(12):150-156,7.
强激光与粒子束2024,Vol.36Issue(12):150-156,7.DOI:10.11884/HPLPB202436.240095

基于EBT3胶片开展电子FLASH放疗剂量测量研究

Study of electron FLASH radiotherapy dose measurement based on EBT3 film

王诗岚 1羊奕伟 1程德琪 2唐镭迅 3吴岱1

作者信息

  • 1. 中国工程物理研究院应用电子学研究所,四川 绵阳 621900
  • 2. 哈尔滨工程大学核科学与技术学院,哈尔滨 150001
  • 3. 南华大学核科学技术学院,湖南 衡阳 421001
  • 折叠

摘要

Abstract

FLASH radiotherapy delivers the entire dose to the target area within milliseconds using ultra-high dose rates,rendering existing online dosimeters essentially ineffective.Currently,radiation-sensitive films are commonly employed for dose measurement.Utilizing an electron accelerator developed by the Institute of Applied Electronics of CAEP,an electron FLASH radiotherapy platform was established to investigate the dose rate range and dose distribution using the EBT3 film's rapid readout method.Experimental results indicate that the rapid readout method of EBT3 films is applicable for dose measurement in electron FLASH radiotherapy,with dose rates ranging from 240 Gy/s to 290 Gy/s at a source-to-skin distance of 100 cm and a depth of 1 cm.Fluctuations in the average energy of the electron beam reaching the surface of the phantom result in dose fluctuations of approximately±5%in the target area.The surface dose distribution meets the requirements of flatness within±5%and symmetry within±3%.

关键词

放射治疗/超高剂量率/EBT3胶片/剂量测量/电子FLASH放疗平台

Key words

radiation therapy/ultra-high dose rate/Gafchromic EBT3/dosimetry/electron FLASH radiotherapy platform

分类

医药卫生

引用本文复制引用

王诗岚,羊奕伟,程德琪,唐镭迅,吴岱..基于EBT3胶片开展电子FLASH放疗剂量测量研究[J].强激光与粒子束,2024,36(12):150-156,7.

基金项目

国家自然科学基金项目(12375318) (12375318)

强激光与粒子束

OA北大核心CSTPCD

1001-4322

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