RISS阻滞在胸腔镜肺癌根治术后镇痛中的临床应用OACSTPCD

Objective:To explore the clinical effect,safety and effectiveness of ultrasound-guided rhomboid intercostal and subserratus plane(RISS)block for postoperative analgesia after thoracoscopic radical resection of lung cancer.Methods:80 lung cancer patients undergoing thoracoscopic radical resection in Chengdu Fifth People's Hospital from Jan-uary 2023 to August 2023 were prospectively collected as research objects.They were divided into two groups by using ran-dom number table:Group R(RISS block+patient controlled intravenous analgesia)and Group C(patient controlled intra-venous analgesia).The primary and secondary outcome indicators in two groups were recorded and compared.The primary outcome indicator was analgesic effect,Visual Analogue Scale(VAS)score for rest and cough 2,6,12,24,and 72 hours af-ter surgery.The secondary outcome indicators included postoperative use of analgesics,postoperative adverse reactions and analgesia satisfaction.Postoperative use of analgesics included the amount of sufentanil used within 24 hours after surgery,the number of effective presses of the analgesia pump and the number of additional rescue analgesia.Adverse reactions during postoperative analgesia included dizziness,lethargy,postoperative nausea and vomiting(PONV),hypotension,urinary reten-tion,etc.Results:The rest and cough VAS scores in Group R were significantly lower than those in Group C 2,6,12,24 and 72 hours after surgery(P＜0.05).The dosage of sufentanil,frequency of effective press of analgesia pump and frequen-cy of additional rescue analgesia in group R were significantly lower than those in group C within 24 hours after surgery(P＜0.05).The incidences of dizziness and PONV in group R were significantly lower than those in group C(P＜0.05).The overall satisfaction over postoperative analgesia in Group R was higher than that in Group C(P＜0.05).Conclusion:Ultra-sound-guided RISS block can provide good postoperative analgesia for thoracoscopic radical resection of lung cancer,reduce the demand for postoperative analgesic drugs and the incidence of postoperative adverse reactions,and improve patient satis-faction over postoperative analgesia.