中风与神经疾病杂志2024,Vol.41Issue(11):969-972,4.DOI:10.19845/j.cnki.zfysjjbzz.2024.0184
脑深部电刺激术对帕金森病患者眼球运动影响的研究进展
Research advances in the effect of deep brain stimulation on eye movement in patients with Parkinson disease
摘要
Abstract
Deep brain stimulation(DBS)has become an established technique for the treatment of neurodegenerative diseases such as Parkinson disease(PD).This technique significantly improves the clinical symptoms of PD patients by directly stimulating specific basal ganglia nuclei with implanted electrodes,but its physiological mechanism of action remains unclear.The control mechanisms of eye movement involve the cerebral cortex and basal ganglia,which are extensively overlapped with the targeted network of DBS,but there are relatively few studies on the combined analysis of DBS and eye movement.This article explores the interaction mechanism between DBS and eye movement control to deeply understand the influence of DBS on eye movement function,which is of great significance for optimizing stimulation parameters and improving therapeutic effect.In addition,these studies provide new perspectives for revealing the mechanism of action of DBS and the pathophysiology of PD.关键词
帕金森病/脑深部电刺激术/眼球运动/术后程控Key words
Parkinson disease/Deep brain stimulation/Eye movement/Postoperative programming分类
临床医学引用本文复制引用
裴晨卉,张亭亭,梁战华,李涛..脑深部电刺激术对帕金森病患者眼球运动影响的研究进展[J].中风与神经疾病杂志,2024,41(11):969-972,4.基金项目
辽宁省教育厅科学研究经费项目(LJKZ0854) (LJKZ0854)