中风与神经疾病杂志2024，Vol.41Issue(11)：973-976,4.DOI:10.19845/j.cnki.zfysjjbzz.2024.0185
帕金森病的脑血流调节研究进展
Research advances in cerebral blood flow regulation in Parkinson disease
摘要
Abstract
Cerebral blood flow directly affects substance metabolism and neural activity in the brain,and it is closely associated with the development and progression of neurodegenerative diseases.The ability for cerebral blood flow regulation directly affects the stability of cerebral blood perfusion,which is an important indicator for evaluating brain function.At present,studies have shown that the reduction in cortical perfusion is closely associated with cognitive decline in patients with Parkinson disease,and orthostatic hypotension often occurs in the late stage of the disease,thereby further increasing the risk of hypoperfusion,which reflects the importance of the ability for cerebral blood flow regulation in Parkinson disease.By reviewing related articles,this article summarizes the mechanism of cerebral blood flow regulation in patients with Parkinson disease,such as cerebral blood flow autoregulation,cerebral vasomotor reactivity,neurovascular coupling,and endothelium-dependent response,so as to provide new ideas and directions for exploring the effect of cerebral blood flow on Parkinson disease.关键词
帕金森病/脑血流自动调节/脑血管舒缩反应/神经血管耦合Key words
Parkinson disease/Cerebral blood flow autoregulation/Cerebral vasomotor reactivity/Neurovascular coupling分类
医药卫生引用本文复制引用
曾景蓉,许保磊,许二赫..帕金森病的脑血流调节研究进展[J].中风与神经疾病杂志,2024,41(11):973-976,4.基金项目
国家重点研发计划(2021YFC2501200) （2021YFC2501200）
