摘要
Abstract
Objective To investigate the application value of high-resolution low-dose CT(HRLDCT)in screening for lung diseases and extra-pulmonary lesions in asymptomatic healthy individuals.Methods A retrospective analysis was performed on the images of 1 940 asymptomatic healthy individuals who underwent chest HRLDCT examination in our hospital from January 2011 to December 2021.Two investigators conducted independent evaluations and recordings of each positive CT sign in all individuals.An analysis of the detection rates of positive CT signs in the entire population,examining their distribution across various gender and age groups was involved in this study.The detection of positive CT signs outside the lung was also investigated.Additionally,the comparative analysis of lung cancer and benign pulmonary nodules detection across various genders and age cohorts were performed.Results A comprehensive count of 1831 individuals exhibited positive CT signs,resulting in an overall detection rate of 94.38%,with identifying a total of 3339 positive CT signs.The positive CT sign with the highest detection rate was benign pulmonary nodule(1 630 cases,84.02%).In 973 male participants,22 cases of lung cancer were detected(2.26%),and 815 cases of benign lung nodules were found(83.73%).In 967 female participants,19 cases of lung cancer were detected(1.96%),and 815 cases of benign lung nodules were identified(84.28%).Statistical analysis revealed no significant difference in the detection rates of lung cancer and benign lung nodules between genders(P=0.64,χ2=0.214).The prevalence of positive CT signs in the lungs demonstrates an upward trend with advancing age.Notably,individuals aged 51-60 exhibit a higher incidence of lung cancer and benign lung nodules.A statistically significant disparity in the detection rates of these conditions is observed between the 51-60 and 61-70 age cohorts(P=0.038,χ2=4.32).In addition,the most frequently detected extrapulmonary positive CT findings were fatty liver,with a total of 497 cases(25.62%),followed by coronary artery calcification with 173 cases(8.90%).Conclusions HRLDCT can be effectively employed in the screening of pulmonary conditions and identification of extra-pulmonary abnormalities during thoracic health assessments,demonstrating considerable clinical significance.关键词
高分辨率低剂量CT/肺癌/肺结节/健康体检/肺部疾病Key words
high-resolution low-dose computed tomography/lung cancer/pulmonary nodule/health examination/pulmonary diseases
