华东师范大学学报（自然科学版）Issue(6)：39-51,13.DOI:10.3969/j.issn.1000-5641.2024.06.004
复杂环境基质中全氟化合物检测方法的优化及应用
Optimization and application of detection methods for perfluorinated compounds in complex environmental matrices
摘要
Abstract
The detection method for perfluorinated compounds(PFASs)and the sample pretreatment process for complex environments were optimized using solid-phase extraction in conjunction with ultra-high performance liquid chromatography-tandem mass spectrometry.This optimized method allowed concurrent extraction and identification of 41 PFASs in diverse environmental matrices.Optimal ion pairs and mass spectrometry parameters for the targets were determined through manual tuning of single standards for instrument optimization.The optimal chromatographic mobile phase was identified as a combination of 2 mmol/L ammonium acetate solution and methanol.Higher recovery rates and shorter extraction times compared to accelerated solvent extraction in the context of sample extraction and purification were found for ultrasonic extraction of solid samples at 30℃ for 10 minutes.The use of a parallel quantitative concentrator for nitrogen evaporation resulted in an average recovery rate of 104.3％,with a process time half as long as the time required for the traditional water bath method.The average recovery rates were 108.2％and 105.5％when using 2 mmol/L ammonium acetate solution(pH=3)and 1 mL of 0.5％ammonia methanol solution for solid-phase extraction column elution and washing,respectively.The optimized method was applied to actual samples(soil,sediment,and water),achieving detection limits of 0.01～0.34 ng,matrix spiking recovery rates of 67.9％～174.9％,and relative standard deviations for parallel samples of 0.03％～28.10％.Overall,the optimized sample preparation method is more time-and solvent-efficient than previous methods,offers better sensitivity and recovery rates,and thus provides a solid technical foundation for large-scale environmental sample detection.关键词
全氟化合物/环境多介质/检测方法/方法应用Key words
perfluoroalkyl substances/environmental multi-media/detection methods/method application分类
资源环境引用本文复制引用
李雨珊,杨静,李晔,杨丁业,丁方方,王余意,刘敏..复杂环境基质中全氟化合物检测方法的优化及应用[J].华东师范大学学报（自然科学版）,2024,(6):39-51,13.基金项目
国家自然科学基金(42230505,41730646) （42230505,41730646）
