解放军医学杂志2024，Vol.49Issue(11)：1244-1250,7.DOI:10.11855/j.issn.0577-7402.0236.2024.0924
库欣病的诊治进展
Advances in the diagnosis and treatment of Cushing's disease
摘要
Abstract
Cushing's disease is a severe endocrine disorder caused by excess secretion of adrenocorticotropic hormone from pituitary.Due to its subtle early clinical manifestations,the diagnosis of Cushing's disease is often delayed,and differentiating it from ectopic adrenocorticotropic hormone syndrome is a challenge.Combined functional tests can improve the diagnostic accuracy of Cushing's disease.The primary treatment for Cushing's disease is surgical removal of pituitary adenoma.However,about 1/3 of patients do not respond or experience recurrence after surgery,necessitating second-line treatments including medication.The development of novel drugs has enhanced the role of pharmacotherapy in the management of Cushing's disease.The review discusses the classic and emerging diagnostic methods and treatment strategies of Cushing's disease to deepen clinicians'understanding of its current treatment status and prospects.关键词
库欣病/异位促肾上腺皮质激素综合征/促肾上腺皮质激素/皮质醇Key words
Cushing's disease/ectopic adrenocorticotropic hormone syndrome/adrenocorticotropic hormone/cortisol分类
医药卫生引用本文复制引用
王岳鹏,李冰,吕朝晖,谷伟军..库欣病的诊治进展[J].解放军医学杂志,2024,49(11):1244-1250,7.基金项目
This work was supported by the Beijing Natural Science Foundation(7232155) 北京市自然科学基金(7232155) （7232155）
