昆明医科大学学报2024，Vol.45Issue(11)：155-160,6.DOI:10.12259/j.issn.2095-610X.S20241101
沙库巴曲缬沙坦治疗糖尿病合并心血管并发症的研究进展
Research Progress in the Treatment of Diabetes Mellitus with Cardiovascular Complications with Sacubitril Valsartan
摘要
Abstract
Diabetes often coexists with cardiovascular complications,which are also a common cause of death in diabetes patients.Therefore,in addition to improving glucose metabolism,it is also necessary to control cardiovascular complications in diabetes patients.Sacubitril valsartan is a novel compound with dual actions of inhibiting neprilysin and angiotensin receptor,and it is commonly used as a heart failure drug in clinical practice.Recent studies suggest that sacubitril valsartan may also have potential metabolic benefits,improving cardiac function while improving glycemic control in diabetes patients,and it is expected to become a drug that can be used routinely in diabetes,bringing cardiovascular and metabolic benefits.This review focuses on the clinical efficacy and metabolic benefits of sacubitril valsartan in the treatment of diabetes patients with cardiovascular diseases.关键词
沙库巴曲缬沙坦/脑啡肽酶/肾素血管紧张素系统/利钠肽/血糖Key words
Sacubitril valsartan/Neprilysin/Renin angiotensin system/Natriuretic peptide/Blood sugar分类
医药卫生引用本文复制引用
陈琳,念馨,蔡红雁..沙库巴曲缬沙坦治疗糖尿病合并心血管并发症的研究进展[J].昆明医科大学学报,2024,45(11):155-160,6.基金项目
国家自然科学基金资助项目(82270372) （82270372）
云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目(202201AY070001-066) （202201AY070001-066）
云南省"兴滇英才支持计划"名医专项基金资助项目(RLMY20220005) （RLMY20220005）
云南省重大疑难疾病中西医临床协作试点基金资助项目(300073) （300073）
昆明医科大学科技创新团队基金资助项目(CXTD202209) （CXTD202209）
