昆明医科大学学报2024，Vol.45Issue(11)：161-165,5.DOI:10.12259/j.issn.2095-610X.S20241123
DDX46在恶性肿瘤发生发展中的作用
The Role of DDX46 in the Occurrence And Development of Malignant Tumors
摘要
Abstract
With the deepening development of molecular biology,people's understanding of the mechanisms of cancer occurrence is becoming increasingly profound.In recent years,DDX46 has been found to be overexpressed in various cancers such as colorectal cancer,esophageal squamous cell carcinoma,and gastric cancer.It can promote the proliferation of various malignant tumor cells,activate invasion and migration,resist cell apoptosis,and participate in the cell cycle.Therefore,it may become a potential target and biomarker for anti-tumor drugs.To provide a more intuitive understanding of the role of DDX46 in cancer,we systematically describe its functions and related mechanisms in various aspects of tumorigenesis and development.It provides a new idea for the research and development of DDX46 targeted drugs.关键词
分子生物学/DDX46/癌症/RNA解旋酶Key words
Molecular biology/DDX46/Cancer/RNA helicase分类
医药卫生引用本文复制引用
霍玉,鞠云鹤,王宇涛,曾雅林,梁俊峰..DDX46在恶性肿瘤发生发展中的作用[J].昆明医科大学学报,2024,45(11):161-165,5.基金项目
国家自然科学基金资助项目(82160562) （82160562）
云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目(202001AC070140) （202001AC070140）
