395例瘢痕疙瘩患者临床分析OA

Objective To investigate the characteristics of lesions and clinical features of ke-loids.Methods This study included a total of 395 patients with keloids who were diagnosed and treated at the Dermatology Department of the Second Hospital of Hebei Medical University between October 2022 and October 2023.Patients'general information,characteristics of onset and treat-ment history were analyzed.Results The male-to-female ratio was 1∶1.04.The peak onset age was between 19～28 years old.The chest(48.35％)and shoulders/back(22.28％)were the two most commonly affected areas.One hundred sixty-two(41.01％)patients had single lesion on single site.Patients with a family history of keloids accounted for 4.30％.Among the 395 pa-tients,74.94％of the patients had not received any treatments,while 25.06％had a history of treatment prior to visiting our clinic.Twelve patients had received multiple or combination modali-ty treatments,and 87 patients had received single modality treatment.Patients who had received previous treatments experienced recurrence.Conclusions Keloids primarily affect young individ-uals,predominantly on the chest and shoulders/back,and mostly present as single lesion on one body site.There are no significant differences in onset sites,clinical classification and lesion sizes between genders.Genetic factors can affect the development of keloids.Patients with keloids are often treated with local drug injection,surgical resection,and other methods.But the recurrence rate is high,indicating a challenge in the treatment of keloids.