皮肤性病诊疗学杂志2024，Vol.31Issue(11)：773-777,5.DOI:10.3969/j.issn.1674-8468.2024.11.008
脐部天疱疮1例
A case of umbilical pemphigus vulgaris
郑航 1谢雅琳 2孙翠翠 1陈文静 2梁云生 2陈永锋1
作者信息
- 1. 安徽医科大学广东皮肤病临床学院||南方医科大学皮肤病医院,广东 广州 510091
- 2. 南方医科大学皮肤病医院,广东 广州 510091
- 折叠
摘要
Abstract
A case of umbilical pemphigus vulgaris is reported.A 37-year-old female presented with a half-year history of repeated oral blood blisters and periumbilical itchy blisters.Dermatolog-ical examination revealed a demarcated annular irregular erosive surface covered with odorless white secretions on the umbilical area.But neither blisters nor erosions were observed in the oral mucosa.PDAI activity scores were 2 points.Pathological examination of skin lesion showed blis-ters in the basal layer and acantholytic cells in the epidermis,and lymphocytic infiltrations in the superficial dermis.Direct immunofluorescence revealed reticular deposition of IgG and C3 in the intercellular space of the spinous layer,without IgM and IgA depostion.The diagnosis was pem-phigus vulgaris.Patient was treated with intramuscular injection of Methotrexate(10 mg)once,and oral methylprednisolone tablets at a dose of 24 mg once daily,in addition to calcium supple-mentation and topical applications of Halometasone and Sodium Fusidate Ointment.After the skin lesion was improved,the patient was discharged.No new lesions occurred during 6-month phone follow-up.关键词
天疱疮/脐部Key words
pemphigus vulgaris/umbilical region引用本文复制引用
郑航,谢雅琳,孙翠翠,陈文静,梁云生,陈永锋..脐部天疱疮1例[J].皮肤性病诊疗学杂志,2024,31(11):773-777,5.
