西南医科大学学报2024，Vol.47Issue(6)：488-493,501,7.DOI:10.3969/j.issn.2096-3351.2024.06.006
乳腺外佩吉特病诊疗进展
Advances in the diagnosis and treatment of extramammary Paget's disease
摘要
Abstract
Extramammary Paget's disease(EMPD)is a rare cutaneous malignancy with a long discovery history,predominantly affecting the elderly.The incidence of EMPD varies significantly across different countries and regions,and overall,it has been rising in parallel with the aging population.The biological behavior of EMPD is typically indolent,and it is often clinically confused with various dermatological conditions.Additionally,the pathogenesis,especially the cellular origin,remains controversial,frequently resulting in a prolonged course and delayed diagnosis.EMPD can be classified into primary and secondary types.Diagnosis and evaluation emphasize biopsy,with attention also required for screening for associated internal malignancies.EMPD has a high recurrence rate and treatment strategies can be broadly categorized into surgical and non-surgical approaches.The former focuses on determining the extent of lesion excision,with intraoperative margin pathology examinations being crucial.Standardized protocols are still lacking for the latter.This ar-ticle reviewed the current state of diagnosis,treatment,and research of EMPD,aiming to provide a reference for clinicians and research-ers involved in this condition.关键词
乳腺外佩吉特病/皮肤恶性肿瘤/外阴/诊断/治疗Key words
Extramammary Paget's disease/Malignant skin tumors/Vulva/Diagnosis/Treatment分类
医药卫生引用本文复制引用
雷攀,解晓都,张鹏,余佳成,杨楠,梁培禾..乳腺外佩吉特病诊疗进展[J].西南医科大学学报,2024,47(6):488-493,501,7.基金项目
重庆市自然科学基金项目(CSTB2023NSCQ-MSX0195) （CSTB2023NSCQ-MSX0195）
重庆市留学人员回国创业创新支持计划(cx2019146) （cx2019146）
