首页|期刊导航|中国伤残医学|加味健脾益肾汤联合促红细胞生成素治疗肾性贫血患者的效果分析

加味健脾益肾汤联合促红细胞生成素治疗肾性贫血患者的效果分析OA

Effect Analysis of Modified Jianpi Yishen Decoction Combined with Erythropoietin in the Treatment Patients of Renal Anemia

中文摘要英文摘要

目的:分析加味健脾益肾汤联合促红细胞生成素(EPO)治疗对肾性贫血患者的影响.方法:选取 2021年 9月—2023年 9月临沭县中医医院收治的 84例肾性贫血患者为研究对象,随机将其分为对照组和研究组,各 42例.对照组采用EPO治疗,研究组在其基础上联合加味健脾益肾汤治疗.对比两组临床疗效、中医证候评分、红细胞参数、铁代谢指标、肾功能及不良反应发生情况.结果:研究组治疗总有效率为 95.24%,高于对照组的 78.57%,差异有统计学意义(P<0.05).治疗后,两组气短懒言、倦怠乏力、纳呆食少、口淡不渴、大便不实评分、血肌酐水平、尿素氮水平均低于治疗前,且研究组均低于对照组,差异均有统计学意义(P<0.05).治疗后,两组血红蛋白、红细胞计数、红细胞压积水平、铁蛋白水平、转铁蛋白饱和度均高于治疗前,且研究组均高于对照组,差异均有统计学意义(P<0.05).研究组不良反应发生率为11.90%,相较于对照组的 19.05%,差异无统计学意义(P>0.05).结论:加味健脾益肾汤联合EPO治疗肾性贫血患者较为有效,其可缓解患者气短懒言、倦怠乏力、纳呆食少、口淡不渴、大便不实的症状,提升红细胞参数与铁代谢,改善肾功能,且未发生严重的不良反应.

Objective:To analyze the effects of modified Jianpi Yishen Decoction combined with erythropoietin(EPO)on patients with renal anemia.Methods:A total of 84 patients with renal anemia treated in Linshu Hospital of Traditional Chinese Medicine from September 2021 to September 2023 were selected as the study objects.They were randomly divided into a control group and a study group,with 42 cases in each group.The control group was treated with EPO,the study group was treated with supplemented Jianpi Yishen Decoction.The clinical efficacy,Traditional Chinese Medicine syndrome score,red blood cell parameters,iron metabolism index,renal function and occurrence of adverse reactions were compared between the two groups.Results:The total effective rate of the study group was 95.24%,which was higher than 78.57%in the control group,the difference was statistically significant(P<0.05).After treatment,the syndrome scores,blood creatinine level,urea nitrogen level of both groups were lower than before treatment,the study group was lower than the control group,the differences were statistically significant(P<0.05).After treatment,hemoglobin,red blood cell count,hematocrit level,ferritin level and transferrin saturation in two groups were higher than before treatment,and the study group was higher than the control group,the differences were statistically significant(P<0.05).The incidence of adverse reactions in the study group was 11.90%,compared with 19.05%in the control group,the difference was not statistically significant(P>0.05).Conclusion:Modified Jianpi Yishen Decoction combined with EPO is more effective in the treatment of patients with renal anemia,which can relieve the symptoms of shortness of breath,lazy speech,fatigue,little food,weak mouth,and insufficient stool,improve red blood cell parameters and iron metabolism,improve renal function,and no serious adverse reactions.

刘铭秋

山东省临沭县中医医院内一科,山东 临沂 276700

中医学

肾性贫血加味健脾益肾汤促红细胞生成素不良反应铁代谢

Renal anemiaAdded Jianpi Yishen DecoctionErythropoietinAdverse reactionsIron metabolism

《中国伤残医学》 2024 (016)

16-19 / 4

10.13214/j.cnki.cjotadm.2024.016.005

评论