中国伤残医学2024，Vol.32Issue(16)：115-118,4.DOI:10.13214/j.cnki.cjotadm.2024.016.031
髓过氧化物酶预警健康及亚健康人群发生急性冠状动脉综合征的应用研究
Application of Myeloperoxidase in Early Warning of Acute Coronary Syndrome in Healthy and Sub-Healthy People
摘要
Abstract
Objective:To investigate the application value of myeloperoxidase(MPO)in early warning of acute coronary syndrome(ACS)in healthy and sub-healthy people.Methods:The data of 90 individuals who underwent physical examination in Ganzhou People's Hospital from May 2021 to May 2023 were retrospectively analyzed.Healthy individuals serving as the control group and sub-health individuals as the research group,each with 45 cases.The levels of MPO,Creatine Kinas isoenzyme and Creatine Kinase in the two groups were measured and analyzed.ROC curve was used to analyze the predictive value of MPO,CK isoenzyme and creatine kinase levels in the occurrence of ACS in sub-healthy people.Results:The levels of MPO,Creatine Kinas isoenzyme and Creatine Kinase in study group were higher than those in control group,and the differences were statistically significant(P＜0.05).ROC curve analysis showed that the area under curve,sensitivity and specificity of MPO level were 0.92,0.93 and 0.88,which were higher than Creatine Kinas isoenzyme and Creatine Kinase levels.Conclusion:Compared with the healthy population,the MPO level of sub-healthy population will increase abnormally,which has important predictive value for the occurrence of ACS in sub-healthy population.By detecting MPO levels,potential cardiovascular problems in sub-healthy people can be found,providing diagnostic basis for early prevention and treatment,and reducing the risk of ACS.关键词
急性冠状动脉综合征/髓过氧化物酶/预测价值/亚健康Key words
Acute coronary syndrome/Myeloperoxidase/Predictive value/Sub-health分类
医药卫生引用本文复制引用
林燕..髓过氧化物酶预警健康及亚健康人群发生急性冠状动脉综合征的应用研究[J].中国伤残医学,2024,32(16):115-118,4.基金项目
赣州市指导性科技计划(GZ2020ZSF186) （GZ2020ZSF186）
