塑料科技2024，Vol.52Issue(11)：117-124,8.DOI:10.15925/j.cnki.issn1005-3360.2024.11.023
顶空-气相色谱-三重四极杆质谱联用法同时测定一次性使用输液器中55种溶剂的残留量
Determination of Residual Quantity of 55 Solvent Compounds in Disposable Infusion Set by Headspace-GC-MS/MS
摘要
Abstract
An analytical method was established for the simultaneous determination of residual quantity of 55 solvent compounds in disposable infusion sets by headspace-gas chromatography-triple quadrupole mass spectrometry(GC-MS/MS).The headspace injection was used to screen the residual quantity of 55 solvent compounds in the infusion set,and the samples were separated on a TG-624Sil MS(60 m×0.25 mm×1.4 μm)column,and the residual quantity of 55 solvent compounds in the infusion set were screened in selected reaction monitoring(SRM)mode,and the 55 solvent compounds were effectively separated within 36 min.The linearities were good in the respective concentration ranges,and the average spiked recoveries were 81.7%～111.7%,with the relative standard deviations(RSDs)of 0.37%～8.66%(n=6),and the limits of detection(LODs)were in the range of 0.1～0.2 μg/L.The method is simple,fast,accurate and efficient,and it can be used for the determination of the residual quantity of the 55 solvent compounds in disposable infusion sets.关键词
溶剂残留量/气相色谱-三重四极杆质谱联用法/一次性输液器Key words
Solvent compounds residual quantity/GC-MS/MS/Disposable infusion set分类
化学化工引用本文复制引用
秦瑶,余秋玲,张永梅,张云冉,龙梅,向壹..顶空-气相色谱-三重四极杆质谱联用法同时测定一次性使用输液器中55种溶剂的残留量[J].塑料科技,2024,52(11):117-124,8.基金项目
重庆市计量质量检测研究院科研计划项目(2023(研)-05) （2023(研）
