饲料研究2024，Vol.47Issue(21)：1-7,7.DOI:10.13557/j.cnki.issn1002-2813.2024.21.001
柠条单宁对高精料育肥羔羊生长性能、血清生化指标及免疫功能的影响
Effects of Caragana Korshinskii tannins on growth performance,serum biochemical index,and immune function of finishing lambs fed high concentrate diet
摘要
Abstract
The experiment aimed to investigate the effects of Caragana korshinskii tannins(CKT)on the growth performance,serum biochemical index,and immune function in finishing lambs fed high concentrate diet.Thirty 3-month-old Dumont crossbred male lambs were randomly divided into five treatment groups with six replicates per group and one sheep per replicate.The sheep were fed a low-concentrate diet(LC group),a high-concentrate diet(HC group),a high-concentrate diet with 0.1％CKT(HC+0.1％CKT group),a high-concentrate diet with 0.2％CKT(HC+0.2％CKT group),and a high-concentrate diet with 0.4％CKT(HC+0.4％CKT group).The pre-test period was 15 days and the formal test period was 45 days.The results showed that compared with HC group,the activities of serum aspartate aminotransferase(AST)and alanine aminotransferase(ALT)in HC+0.1％CKT and HC+0.2％CKT groups were significantly decreased(P＜0.05),and the serum urea nitrogen(BUN)and creatinine(CRE)concentrations in HC+0.1％CKT group were significantly decreased(P＜0.05).Serum cholesterol(TC)content in HC+0.2％CKT group was significantly decreased(P＜0.05).Compared with the HC group,mRNA expression levels of interleukin-1β(IL-1β),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),Toll-like receptor 4(TLR-4),bone marrow differentiation factor 88(MyD88),and nuclear transcription factor-κB(NF-κB)in peripheral blood lymphocytes and serum IL-1β and interleukin-4(IL-4)were significantly decreased(P＜0.05),the mRNA expression of IL-4 was significantly increased(P＜0.05)in HC+0.1％CKT,HC+0.2％CKT,and HC+0.4％CKT groups.Serum immunoglobulin G(IgG),immunoglobulin M(IgM),and interleukin-10(IL-10)levels in HC+0.2％CKT and HC+0.4％CKT groups were significantly increased(P＜0.05).The results show that the appropriate dosage of CKT can improve the immune function of lambs and alleviate the organ damage caused by high concentrate,and the appropriate supplemental level of CKT was 0.2％under the experimental conditions.关键词
柠条单宁/高精料饲粮/羔羊/生长性能/免疫调节Key words
Caragana korshinskii tannins/high concentrate diet/lambs/growth performance/immune modulation分类
农业科技引用本文复制引用
陈治宇,牛晓雨,李慧,王雅宁,李瑞雪,刘沛楠,邢媛媛,李大彪..柠条单宁对高精料育肥羔羊生长性能、血清生化指标及免疫功能的影响[J].饲料研究,2024,47(21):1-7,7.基金项目
国家自然科学基金项目(项目编号:32360842) （项目编号:32360842）
