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自拟催情微粉的质控及药效学研究

马霞 张国祖 张继臣 韩烨 王林 王兴涛 马仲彬 王德云 郭振环

畜牧与兽医2024,Vol.56Issue(12):35-40,6.
畜牧与兽医2024,Vol.56Issue(12):35-40,6.

自拟催情微粉的质控及药效学研究

Study on the quality standards and pharmacodynamics of self-formulated aphrodisiac micropowder

马霞 1张国祖 1张继臣 2韩烨 2王林 3王兴涛 3马仲彬 3王德云 4郭振环1

作者信息

  • 1. 河南省康星药业股份有限公司,河南 郑州 451464||河南牧业经济学院,河南 郑州 450046
  • 2. 河南牧业经济学院,河南 郑州 450046
  • 3. 河南省康星药业股份有限公司,河南 郑州 451464
  • 4. 南京农业大学,江苏 南京 210095
  • 折叠

摘要

Abstract

This study was to establish a quality standard of self-formulated aphrodisiac powder and verify its pharmacological effects in pro-moting reproductive system development.The thin layer chromatography method was used to determine the content of angelica sinensis and α-cyperone.The content of icariin was determined by High-performance liquid chromatography.And pharmacodynamics of self-formulated aph-rodisiac powder was determined using the mouse uterine weight method.The results showed that,in chromatography,the test samples had the same color with angelica sinensis and α-cyperone,while the negative control samples did not.The content determination results showed that icariin had good linearity(R2=0.997 5),at an average recovery rate of 98.87%.The content of icariin in 10 batches was at an average of 0.15%.The content limit of icariin was no less than 0.12%.Compared with the blank control group,daily administration of micropowder at doses of 24 g/kg and 8 g/kg could significantly improve the uterine organ coefficient of mice.The results indicated that the detection method was accurate and reliable,and it could be used for the quality evaluation of self-formulated aphrodisiac powder.It had the effect of promoting the development of the reproductive system in mice.The established detection method was feasible and stable,and self-formulated aphrodisi-ac powder had the effect of promoting the development of the mouse reproductive system.

关键词

自拟催情微粉/α-香附酮/鉴别/淫羊藿苷/含量测定/药效

Key words

self-formulated aphrodisiac micropowder/α-cyperone/identification/icariin/content determination

分类

农业科技

引用本文复制引用

马霞,张国祖,张继臣,韩烨,王林,王兴涛,马仲彬,王德云,郭振环..自拟催情微粉的质控及药效学研究[J].畜牧与兽医,2024,56(12):35-40,6.

基金项目

校企合作项目(L6010036) (L6010036)

河南牧业经济学院兽医学重点学科项目(XJXK202202) (XJXK202202)

畜牧与兽医

OA北大核心CSTPCD

0529-5130

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