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Increasing the tumour targeting of antitumour drugs through anlotinib-mediated modulation of the extracellular matrix and the RhoA/ROCK signalling pathway

Xuedan Han Jialei Liu Yidong Zhang Eric Tse Qiyi Yu Yu Lu Yi Ma Lufeng Zheng

药物分析学报（英文）2024，Vol.14Issue(8)：1205-1221,17.

药物分析学报（英文）2024，Vol.14Issue(8)：1205-1221,17.DOI:10.1016/j.jpha.2024.100984

Increasing the tumour targeting of antitumour drugs through anlotinib-mediated modulation of the extracellular matrix and the RhoA/ROCK signalling pathway

Xuedan Han ¹Jialei Liu ²Yidong Zhang ¹Eric Tse ³Qiyi Yu ¹Yu Lu ¹Yi Ma ²Lufeng Zheng¹

作者信息

1. School of Life Science and Technology,China Pharmaceutical University,Nanjing,211198,China
2. Department of Biomedical Engineering,School of Engineering,China Pharmaceutical University,Nanjing,211198,China
3. Sino Biopharmaceutical Group Limited,Beijing,100026,China
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摘要

关键词

Anlotinib/Extracellular matrix/Interstitial fluid pressures/Tumour solid pressure/RhoA/ROCK

Key words

Anlotinib/Extracellular matrix/Interstitial fluid pressures/Tumour solid pressure/RhoA/ROCK

引用本文复制引用

Xuedan Han,Jialei Liu,Yidong Zhang,Eric Tse,Qiyi Yu,Yu Lu,Yi Ma,Lufeng Zheng..Increasing the tumour targeting of antitumour drugs through anlotinib-mediated modulation of the extracellular matrix and the RhoA/ROCK signalling pathway[J].药物分析学报（英文）,2024,14(8):1205-1221,17.

基金项目

This work was supported by the National Natural Science Foundation of China(Grant No.:82173842)and the Priority Aca-demic Program Development(PAPD)of Jiangsu Higher Education Institutions,China.We thank Chia Tai Tianqing Pharmaceutical Group Co.,Ltd.for providing anlotinib,penpulimab,and TQB2450. （Grant No.:82173842）

药物分析学报（英文）

ISSN：2095-1779

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