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Targeted delivery of rosuvastatin enhances treatment of hyperhomocysteinemia-induced atherosclerosis using macrophage membrane-coated nanoparticles

Dayue Liu Shengchao Ma Jiantuan Xiong Yinju Hao Guizhong Li Bin Liu Huiping Zhang Yideng Jiang Anning Yang Yulin Li Zhenxian Li Peidong You Hongwen Zhang Shangkun Quan Yue Sun Yaling Zeng

药物分析学报（英文）2024，Vol.14Issue(9)：1301-1319,19.

药物分析学报（英文）2024，Vol.14Issue(9)：1301-1319,19.DOI:10.1016/j.jpha.2024.01.005

Targeted delivery of rosuvastatin enhances treatment of hyperhomocysteinemia-induced atherosclerosis using macrophage membrane-coated nanoparticles

Dayue Liu ¹Shengchao Ma ¹Jiantuan Xiong ²Yinju Hao ³Guizhong Li ¹Bin Liu ⁴Huiping Zhang ⁵Yideng Jiang ¹Anning Yang ⁶Yulin Li ¹Zhenxian Li ⁷Peidong You ¹Hongwen Zhang ¹Shangkun Quan ¹Yue Sun ⁸Yaling Zeng¹

作者信息

1. Department of Pathophysiology,School of Basic Medical Sciences,Ningxia Medical University,Yinchuan,750004,China||NHC Key Laboratory of Metabolic Cardiovascular Diseases Research,Ningxia Medical University,Yinchuan,750004,China||Ningxia Key Laboratory of Vascular Injury and Repair Research,Ningxia Medical University,Yinchuan,750004,China
2. NHC Key Laboratory of Metabolic Cardiovascular Diseases Research,Ningxia Medical University,Yinchuan,750004,China||Ningxia Key Laboratory of Vascular Injury and Repair Research,Ningxia Medical University,Yinchuan,750004,China
3. NHC Key Laboratory of Metabolic Cardiovascular Diseases Research,Ningxia Medical University,Yinchuan,750004,China||General Hospital of Ningxia Medical University,Yinchuan,750004,China
4. Department of Pathophysiology,School of Basic Medical Sciences,Ningxia Medical University,Yinchuan,750004,China||College of Biology,Hunan University,Changsha,410082,China||Hunan Provincial Maternal and Child Health Care Hospital,Changsha,410000,China
5. General Hospital of Ningxia Medical University,Yinchuan,750004,China||College of Biology,Hunan University,Changsha,410082,China||Hunan Provincial Maternal and Child Health Care Hospital,Changsha,410000,China
6. Department of Pathophysiology,School of Basic Medical Sciences,Ningxia Medical University,Yinchuan,750004,China||General Hospital of Ningxia Medical University,Yinchuan,750004,China||College of Biology,Hunan University,Changsha,410082,China
7. Hunan University of Chinese Medicine,First Clinical College of Traditional Chinese Medicine,Changsha,410007,China
8. NHC Key Laboratory of Metabolic Cardiovascular Diseases Research,Ningxia Medical University,Yinchuan,750004,China||General Hospital of Ningxia Medical University,Yinchuan,750004,China||College of Biology,Hunan University,Changsha,410082,China
折叠

摘要

关键词

Homocysteine/Atherosclerosis/Macrophage membrane/Prussian blue nanoparticles/Rosuvastatin/Gut microbes

Key words

Homocysteine/Atherosclerosis/Macrophage membrane/Prussian blue nanoparticles/Rosuvastatin/Gut microbes

引用本文复制引用

Dayue Liu,Shengchao Ma,Jiantuan Xiong,Yinju Hao,Guizhong Li,Bin Liu,Huiping Zhang,Yideng Jiang,Anning Yang,Yulin Li,Zhenxian Li,Peidong You,Hongwen Zhang,Shangkun Quan,Yue Sun,Yaling Zeng..Targeted delivery of rosuvastatin enhances treatment of hyperhomocysteinemia-induced atherosclerosis using macrophage membrane-coated nanoparticles[J].药物分析学报（英文）,2024,14(9):1301-1319,19.

基金项目

This study was supported by the National Natural Science Foundation of China(Grant Nos.:U21A20343,82160088,81870225,81870332,81700404,82271626,and 82260088) （Grant Nos.:U21A20343,82160088,81870225,81870332,81700404,82271626,and 82260088）

the Natural Sci-ence Foundation of Ningxia Autonomous Region,China(Grant Nos.:2020AAC02021,2020AAC02038,and 2022AAC05025) （Grant Nos.:2020AAC02021,2020AAC02038,and 2022AAC05025）

the Key Research and Development Projects in Ningxia Autonomous Re-gion,China(Grant Nos.:2020BFH02003,2021BEG02033,2020BEG03008,and 2022BFH02013) （Grant Nos.:2020BFH02003,2021BEG02033,2020BEG03008,and 2022BFH02013）

the Basic Scientific Research Operating Expenses from the Public Welfare Research Institutes at the Central Level of the Chinese Academy of Medical Sciences,China(Grant No.:2019PT330002) （Grant No.:2019PT330002）

the Ningxia Science and Tech-nology Leading Talent Project,China(Grant No.:KJT2017007) （Grant No.:KJT2017007）

the Natural Science Foundation of Hunan Province,China(Grant No.:2022JJ40698),the School-level Special Talent Launching Project of Ningxia Medical University,China(Grant No.:XT2018015),and the Open Bidding for Selecting the Best Candidates Program of Ningxia Medical University,China(Grant No.:XJKF230106). （Grant No.:2022JJ40698）

药物分析学报（英文）

ISSN：2095-1779

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