首页|期刊导航|药物分析学报(英文)|"Small is beautiful"-Examining reliable determination of low-abundant therapeutic antibody glycovariants
药物分析学报(英文)2024,Vol.14Issue(10):1435-1449,15.DOI:10.1016/j.jpha.2024.100982
"Small is beautiful"-Examining reliable determination of low-abundant therapeutic antibody glycovariants
"Small is beautiful"-Examining reliable determination of low-abundant therapeutic antibody glycovariants
摘要
关键词
Glycosylation/Mass spectrometry/Monoclonal antibodies/Abundance profiling/Minor glycovariants/Multi-level analysis/Data integrationKey words
Glycosylation/Mass spectrometry/Monoclonal antibodies/Abundance profiling/Minor glycovariants/Multi-level analysis/Data integration引用本文复制引用
Katharina Böttinger,Christof Regl,Veronika Schäpertöns,Erdmann Rapp,Therese Wohlschlager,Christian G.Huber.."Small is beautiful"-Examining reliable determination of low-abundant therapeutic antibody glycovariants[J].药物分析学报(英文),2024,14(10):1435-1449,15.基金项目
Acknowledgments go to Simon Obermaier for initial data treatment as part of his Bachelor thesis.The authors would furthermore like to acknowledge Wolfgang Esser-Skala for providing fragquaxi,MoFi,and CAFOG to the scientific community.This research was funded in whole or in part by the Austrian Sci-ence Fund(FWF)(FG 1201 N,"DigiTherapeutX"],.Figures were created in Inkscape(v1.3.1).Fig.S2 provides an explanation of the used symbol nomenclature and monosaccharide abbreviations. (FWF)