Tetrandrine targeting SIRT5 exerts anti-melanoma properties via inducing ROS,ER stress,and blocked autophagy
Yacong Ji Qian Li Huanrong Hu Hongjuan Cui Yaling Liu Chongyang Li Sicheng Wan Zhen Dong Chaolong Liu Leiyang Guo Shaomin Shi Mingxin Ci Minghao Xu
Tetrandrine targeting SIRT5 exerts anti-melanoma properties via inducing ROS,ER stress,and blocked autophagy
Tetrandrine targeting SIRT5 exerts anti-melanoma properties via inducing ROS,ER stress,and blocked autophagy
摘要
关键词
Melanoma/Tetrandrine/Sirtuin 5(SIRT5)/Mitophagy/Cytoskeletal protein depolymerization/Reactive oxygen species(ROS)Key words
Melanoma/Tetrandrine/Sirtuin 5(SIRT5)/Mitophagy/Cytoskeletal protein depolymerization/Reactive oxygen species(ROS)引用本文复制引用
Yacong Ji,Qian Li,Huanrong Hu,Hongjuan Cui,Yaling Liu,Chongyang Li,Sicheng Wan,Zhen Dong,Chaolong Liu,Leiyang Guo,Shaomin Shi,Mingxin Ci,Minghao Xu..Tetrandrine targeting SIRT5 exerts anti-melanoma properties via inducing ROS,ER stress,and blocked autophagy[J].药物分析学报(英文),2024,14(10):1468-1483,16.基金项目
This work was supported by funding from Natural Science Foundation of China(Grant Nos.:82372519 and 81902664),the Postdoctoral Fellowship Program of CPSF(Grant No.:GZB20240544),the China Postdoctoral Science Foundation(Grant No.:2024M752432),the Natural Science Foundation of Hebei Province(Grant Nos.:H2022206368 and H2022206446),Medical Science Research Program of the Hebei Provincial Health Com-mission(Grant No.:20241603),and Pilot Program of Southwest University(Program No.:SWU-XDZD22006).We also thanked Jifu Li from the College of Sericulture and Textile and Biomass Science of Southwest University for the assistance during the use of the confocal fluorescence microscope(FV1000,Olympus,Japan). (Grant Nos.:82372519 and 81902664)