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Deep learning-based drug screening for the discovery of potential therapeutic agents for Alzheimer's disease

Tong Wu Ruimei Lin Pengdi Cui Jie Yong Heshui Yu Zheng Li

药物分析学报(英文)2024,Vol.14Issue(10):1514-1526,13.
药物分析学报(英文)2024,Vol.14Issue(10):1514-1526,13.DOI:10.1016/j.jpha.2024.101022

Deep learning-based drug screening for the discovery of potential therapeutic agents for Alzheimer's disease

Deep learning-based drug screening for the discovery of potential therapeutic agents for Alzheimer's disease

Tong Wu 1Ruimei Lin 1Pengdi Cui 1Jie Yong 1Heshui Yu 2Zheng Li3

作者信息

  • 1. College of Pharmaceutical Engineering of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin,301617,China
  • 2. College of Pharmaceutical Engineering of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin,301617,China||State Key Laboratory of Component-Based Chinese Medicine,Tianjin,301617,China||Haihe Laboratory of Modern Chinese Medicine,Tianjin,301617,China
  • 3. College of Pharmaceutical Engineering of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin,301617,China||State Key Laboratory of Component-Based Chinese Medicine,Tianjin,301617,China||Haihe Laboratory of Modern Chinese Medicine,Tianjin,301617,China||National Key Laboratory of Chinese Medicine Modernization,Tianjin,301617,China
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摘要

关键词

Alzheimer's disease/Deep learning models/Drug screening/Kaixinsan formula/Acetylcholinesterase/Monoamine oxidase-A

Key words

Alzheimer's disease/Deep learning models/Drug screening/Kaixinsan formula/Acetylcholinesterase/Monoamine oxidase-A

引用本文复制引用

Tong Wu,Ruimei Lin,Pengdi Cui,Jie Yong,Heshui Yu,Zheng Li..Deep learning-based drug screening for the discovery of potential therapeutic agents for Alzheimer's disease[J].药物分析学报(英文),2024,14(10):1514-1526,13.

基金项目

This work was supported by the Science and Technology Project ofHaihe Laboratory of Modern Chinese Medicine,China(Grant No.:22HHZYSS00003)and the Science and Technology Program of Tianjin,China(Grant No.:22ZYJDSS00100).The authors would like to thank the support from Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medi-cine,China(Grant No:ZYYCXTD-D-202002).The authors would like to thank to Prof.Chunhua Wang from Foshan University,Foshan,China for his guidance on this work. (Grant No.:22HHZYSS00003)

药物分析学报(英文)

2095-1779

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