中国动物检疫2024，Vol.41Issue(11)：43-49,7.DOI:10.3969/j.issn.1005-944X.2024.11.008
羊布鲁氏菌病生物安全相关风险因素及群流行率Meta分析
Meta-analysis on Biosafety Risk Factors and Herd Prevalence of Ovine Brucellosis
摘要
Abstract
In order to comprehensively and quantitatively evaluate biosafety risk factors related to ovine brucellosis transmission and its herd true prevalence(TPh),articles on cross-sectional and case-control studies were selected from databases both in Chinese and English languages,the risk factors of ovine brucellosis transmission was quantitatively evaluated using dichotomous variable Meta-analysis,and the TPh of ovine brucellosis was evaluated using single proportion Meta-analysis,followed by article sensitivity analysis.Five articles were included in the evaluation of ovine brucellosis risk factors,from which 8 risk factors were selected,and 8 articles were considered in the TPh.The most significant risk factor spreading brucellosis was mixed feeding with outsourced sheep,with a combined OR value of 11.88,then were the sheep introduced within one-year(OR=4.80),non-disinfection on lambing premises(OR=4.40)and shared/exchanged stud rams(OR=3.02),P＜0.05;and the potential risk factors(P＞0.05)included brokers entering sheep pens within one year(OR=4.21),non-disinfection at entrance to the farm(OR=2.20),untreated aborted ewes(OR=2.06)and mixing with other animals(OR=1.09).The TPh was 22%(95%CI:5%-39%)in northern region,and 0-3%(95%CI:0-6%)in southern region,the combined prevalence rate was 11%(95%CI:6%-17%).In conclusion,it was recommended to strengthen biosafety risk management on sheep farms with a priority to control of the risk factors of ovine brucellosis transmission and concern about potential risk factors,to improve supervision over sheep transportation,to implement targeted prevention and control strategies,and to facilitate prevention and purification of Brucellosis among animals.关键词
布鲁氏菌病/风险因素/生物安全/Meta分析/羊Key words
brucellosis/risk factor/Meta-analysis/sheep分类
农业科技引用本文复制引用
王新,白东宁,李俊生,吴洪涛,薛佳佳,李扬帆,徐琨,张涛,刘健,张靖飞,刘贺,冯鹏,高娟,吴萌萌,石龙飞..羊布鲁氏菌病生物安全相关风险因素及群流行率Meta分析[J].中国动物检疫,2024,41(11):43-49,7.基金项目
陕西省省科学技术厅重点项目(2020NY-035) （2020NY-035）
西安市科技计划项目(创新能力强基计划)(22YXYJ0036) （创新能力强基计划）
西安市科学技术局项目[201806115YF03NC11(1)] （1）
西安市卫健委科研人才项目(2022yb19) （2022yb19）
陕西省第一期兽医现场流行病学培训项目(SN-FETPV) （SN-FETPV）
