浓缩生长因子联合牙周加速成骨正畸术对薄龈型患者牙周软硬组织改建效果研究OACSTPCD

Objective To study the effect of concentrated growth factor(CGF)combined with periodontally accelerated osteogenic orthodontics(PAOO)on periodontal soft and hard tissue reconstruction in the lower anterior teeth of patients of thin gingival phenotype.Methods Twenty patients of thin gingival phenotype(118 lower anterior teeth)were select-ed,who attended the orthodontic department of Hefei Stomatological Hospital and were referred to the periodontal depart-ment for PAOO in the lower anterior region from January 2023 to April 2024,and they were divided into a study group(10 cases,58 lower anterior teeth)and a control group(10 cases,60 lower anterior teeth)by using a randomised numeri-cal table method.The study group was implanted with CGF gel and Bio-Oss bone powder at a mass ratio of 1:1,covered with a CGF membrane+collagen membrane during the PAOO procedure,and the control group was implanted with Bio-Oss bone powder only,covered with a collagen membrane during the procedure.Changes in probing depth(PD),bleeding index(BI),gingival recession depth(RD),keratinised gingival width,gingival thickness,and labial mid-root bone thickness were compared between the 2 groups preoperatively and 6 months postoperatively.Results Preoperatively and at 6 months postoperatively,there was no statistically significant difference in PD,BI or RD between the study group and the control group(all P＞0.05).At 6 months postoperatively,the bone thickness in the labial side of the mid-root increased by(1.14±0.24)mm and(1.03±0.26)mm,and the gingival thickness increased by(0.35±0.15)mm and(0.17±0.15)mm in the study group and the control group,respectively,compared with the preoperative period;the difference in the increase in the thickness of the bone in the labial side of the mid-root and the gingival thickness in the 2 groups was statistically significant(t val-ues being 2.340,6.388,both P＜0.05).The keratinised gingival width also increased in both groups compared to the pre-operative period,but the difference was not statistically significant when comparing the amount of increase(P＞0.05).At 6 months postoperatively,there were 38 lower anterior teeth with gingival thickness＞1 mm(65.5％)in the study group and 17 lower anterior teeth with gingival thickness＞1 mm(28.3％)in the control group,and the difference between the two was statistically significant(x2=16.386,P＜0.001).Conclusion CGF applied to the PAOO procedure improves the periodontal phenotype in patients of thin gingival phenotype and enhances the postoperative periodontal soft and hard tissue reconstruction of the lower anterior teeth.