中国实用内科杂志2024，Vol.44Issue(11)：890-895,6.DOI:10.19538/j.nk2024110103
21-羟化酶缺乏症的围孕期管理
Peri-pregnancy management of 21 hydroxylase deficiency
杨海燕 1秦映芬1
作者信息
- 1. 广西医科大学第一附属医院内分泌科,广西南宁 530021
- 折叠
摘要
Abstract
The 21-hydroxylase deficiency(21-OHD)is the most common type of congenital adrenal hyperplasia.Although women with 21-OHD have declined fertility,they are still able to conceive.Both parties preparing for pregnancy should undergo genetic testing and consult genetic experts before pregnancy.If necessary,the methods such as in vitro fertilization and preimplantation genetic testing should be used to achieve optimal fertility.The 21-OHD women need to adjust glucocorticoids and mineralocorticoids before and during pregnancy,as well as on and after delivery,and postpartum,and should avoid adrenal crisis.We also have corresponding recommendations for monitoring indicators,prenatal diagnosis and treatment,and postpartum management during the perinatal period for 21-OHD female.The entire perinatal period requires experienced endocrinology,obstetrics,and genetic counseling experts to jointly manage.关键词
21-羟化酶缺乏症/生育/妊娠/产前治疗/糖皮质激素Key words
21-hydroxylase deficiency/fertility/pregnancy/prenatal therapy/glucocorticoid分类
医药卫生引用本文复制引用
杨海燕,秦映芬..21-羟化酶缺乏症的围孕期管理[J].中国实用内科杂志,2024,44(11):890-895,6.
