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血清β-catenin与心房颤动预后关系研究

张溪林 王昊 白英

中国实用内科杂志2024,Vol.44Issue(11):944-946,3.
中国实用内科杂志2024,Vol.44Issue(11):944-946,3.DOI:10.19538/j.nk2024110113

血清β-catenin与心房颤动预后关系研究

Study on the relationship between serum β-catenin and the prognosis of atrial fibrillation

张溪林 1王昊 2白英1

作者信息

  • 1. 首都医科大学附属北京同仁医院心血管中心,北京 100005
  • 2. 北京市糖尿病研究所首都医科大学附属北京同仁医院,北京 100005
  • 折叠

摘要

Abstract

Objective To explore the relationship between serum β-catenin and the prognosis of AF.Methods A total of 147 AF patients were enrolled,who were treated in Beijing Tongren Hospital from September 2021 to January 2024.The mean age was(70.59±11.03)Univariate and multivariate and there were 59(40.1%)female:59 patients.Serum β-catenin was detected by Enzyme-Linked Immunosorbent Assay(ELISA).The logistic regression were used to explore the relationship between β-catenin and the prognosis of AF.Results The logistic regression analysis showed that serum β-catenin was negatively correlated with the occurrence of AMI(adjusted OR 0.87,95%confidence interval:0.77-0.99,P=0.03)and positively associated with risk of major bleeding(adjusted OR 1.17,95%CI 1.02-1.35,P=0.03),but had no correlation with the occurrence of stroke and/or systematic embolismor,pulmonary embolism.Conclusion Serum β-catenin is negatirely associated with the occurrence of AMI and positirely correlated with the occurrence of major bleeding in the AF patients.

关键词

心房颤动/β-catenin/急性心肌梗死/大出血

Key words

atrial fibrillation/β-catenin/acute myocardial infarction/major bleeding

分类

医药卫生

引用本文复制引用

张溪林,王昊,白英..血清β-catenin与心房颤动预后关系研究[J].中国实用内科杂志,2024,44(11):944-946,3.

基金项目

北京市属医院科研培育计划项目(PX2023006) (PX2023006)

中国实用内科杂志

OA北大核心CSTPCD

1005-2194

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