中国实用外科杂志2024,Vol.44Issue(11):1295-1299,1305,6.DOI:10.19538/j.cjps.issn1005-2208.2024.11.21
经皮经肝胆道造瘘取石术治疗复发性肝内胆管结石疗效研究
Efficacy analysis of percutaneous transhepatic biliary fistulation lithotripsy for the treatment of recurrent hepatolithiasis
摘要
Abstract
Objective To explore the clinical efficacy of percutaneous transhepatic biliary fistula(PTBF)in treating recurrent intrahepatic bile duct stones.Methods A retrospective analysis was conducted on the clinical data of 63 patients with recurrent intrahepatic bile duct stones treated at Mengchao Hepatobiliary Hospital of Fujian Medical University from January 2021 to June 2023.The patients were divided into the surgical group(44 cases)and the PTBF group(19 cases),according to different lithotomy methods.The baseline data,perioperative changes of parameters and surgery conditions were compared between the two groups.Results There were no significant differences in preoperative baseline characteristics such as gender,age,laboratory indices,Child-Pugh classification of liver function,and complexity of intrahepatic bile duct stones between the two groups(P>0.05).The complete stone removal rate showed no significant difference between the surgical group and the PTBF group(75.0%vs.78.9%,P>0.999).The one-time complete stone removal rate in the surgical group was significantly higher than in the PTBF group,and the difference was statistically significant(93.9%vs.6.7%,P<0.001).Postoperatively,the PTBF group had better outcomes regarding white blood cell count,liver function indices,and complication rates than the surgical group,with significant differences(P<0.05).The changes in pre-and post-operative white blood cell count,hemoglobin,platelet count,alanine amino-transferase,aspartate transaminase,and prothrombin time were smaller in the PTBF group than in the surgical group,with significant differences(P<0.05).Conclusion PTBF is not inferior to traditional surgery in terms of surgical success rate and complete stone removal rate for recurrent intrahepatic bile duct stones.Additionally,PTBF has a lower complication rate,less trauma,and faster recovery,making it an important supplementary treatment to traditional surgery.关键词
肝内胆管结石/经皮经肝胆道造瘘取石术/胆道外科手术/临床疗效Key words
recurrent hepatolithiasis/percutaneous transhepatic biliary fistulation lithotripsy/biliary tract surgery/clinical effectiveness分类
医药卫生引用本文复制引用
黄鑫,罗顺峰,刘红枝,黄起桢,林科灿,方国旭,黄志东,曾永毅..经皮经肝胆道造瘘取石术治疗复发性肝内胆管结石疗效研究[J].中国实用外科杂志,2024,44(11):1295-1299,1305,6.基金项目
福州市临床重点专科建设项目(No.20230101) (No.20230101)