摘要
Abstract
Objective:To investigate the clinical effect of low intensity pulsed ultrasonic wave and low energy shock wave in the treatment of patients with vascular erectile dysfunction.Method:In this study,118 patients with vascular erectile dysfunction admitted to Affiliated Nanhua Hospital,University of South China from October 2022 to October 2023 were selected as research objects and randomly divided into observation group(n=59)and control group(n=59).The observation group was treated with low intensity pulsed ultrasonic wave,and the control group was treated with low energy shock wave.The ultrasound parameters of arterial and venous erectile dysfunction,serum factors levels,clinical efficacy and sexual life satisfaction were compared between two groups.Result:Before treatment,there were no significant differences in color Doppler ultrasonography parameters of arterial erectile dysfunction between the two groups(P>0.05).After treatment,the peak systolic velocity(PSV)increased and the end diastolic velocity(EDV)decreased in both groups,PSV in observation group was higher than that in control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in color Doppler ultrasonography parameters of venous erectile dysfunction between the two groups(P>0.05).After treatment,the PSV and resistance index(RI)increased and the EDV decreased in both groups,PSV and RI in observation group were higher than those in control group,EDV was lower than that in control group,the differences were statistically significant(P<0.05).3 days after treatment,vascular endothelial growth factor(VEGF)and angiopoietin Ⅰ(ANGⅠ)levels in observation group were higher than those in control group,the differences were statistically significant(P<0.05).3 days after treatment,angiopoietin Ⅱ(ANGⅡ)in both groups were significantly lower than those before treatment,and that in the observation group was lower than that the control group,the differences were statistically significant(P<0.05).3 days after treatment,there was no significant difference in brain-derived neurotrophic factor(BDNF)between the two groups(P>0.05).The total effective rate of observation group(96.61%)was higher than that of control group(84.75%)(P<0.05).The sexual life satisfaction of observation group(94.92%)was higher than that of control group(81.36%)(P<0.05).Conclusion:Compared with low energy shock wave therapy,low intensity pulsed ultrasonic wave therapy for vascular erectile dysfunction can promote the balance and recovery of patients'arteriovenous blood flow,promote the regeneration of blood vessels,and improve the therapeutic effect and sexual life satisfaction.关键词
低强度脉冲超声波/低能量冲击波/血管性勃起功能障碍Key words
Low intensity pulsed ultrasonic wave/Low energy shock wave/Vascular erectile dysfunction
