中国耳鼻咽喉头颈外科2024，Vol.31Issue(11)：727-731,5.DOI:10.16066/j.1672-7002.2024.11.010
嗜酸性粒细胞百分比和鼻内镜评分对慢性鼻窦炎伴鼻息肉并发哮喘患者复发的预测价值
Predictive value of eosinophil percentage and nasal endoscopy score for recurrence in patients with chronic sinusitis with nasal polyps complicating asthma
摘要
Abstract
[ABSTRACT]OBJECTIVE To analyze the risk factors for relapse in patients with chronic rhinosinusitis with nasal polyps(CRSwNP)combined with asthm and provide favorable information for precise treatment and healthy prognosis of patients with CRSwNP combined with asthma.METHODS The clinical data of 161 patients with chronic rhinosinusitis with nasal polyps(CRSwNP)combined with asthm who underwent endoscopic surgery at the Department of Otolaryngology Head and Neck Surgery,Yantai Yuhuanding Hospital,affiliated to Qingdao University,from January 2016 to June 2021 were selected.Based on Lasso's Cox regression analysis and multifactorial Cox regression analysis,the associated risk factors were investigated,and the area under curve(AUC)was calculated to determine the performance of the model.Finally,the Kaplan-Meier(K-M)curves were plotted for the relevant influencing factors.RESULTS The Age[HR(95%CI):0.96(0.948-0.98),P<0.001],gender[HR(95%CI):1.94(1.21-3.14),P=0.006],tissue eosinophil percentage[HR(95%CI):1.01(1.01-1.02),P=0.004],and endoscopic nasal polyp score[HR(95%CI):0.86(0.78-0.96),P=0.005]were highly correlated with recurrence in patients with CRSwNP combined with asthma.Patients with CRSwNP combined with asthma had a higher likelihood of relapse after treatment when the tissue Eos%was>21.28%and the endoscopic nasal polyp score was>4.CONCLUSION The age,gender,tissue eosinophil percentage and endoscopic nasal polyp score are independent risk factors for disease recurrence in patients with CRSwNP combined with asthma.关键词
鼻窦炎/鼻息肉/哮喘症/嗜酸细胞/内窥镜检查/鼻内镜评分/鼻息肉复发Key words
Sinusitis/Nasal Polyps/Asthma/Eosinophils/Endoscopy/nasal endoscopy score/nasal polyp recurrence引用本文复制引用
刘会芳,姚依松,王晶妍,王建伟,杨玉娟,张宇,宋西成..嗜酸性粒细胞百分比和鼻内镜评分对慢性鼻窦炎伴鼻息肉并发哮喘患者复发的预测价值[J].中国耳鼻咽喉头颈外科,2024,31(11):727-731,5.基金项目
国家自然科学面上项目基金(82271146、82271147) （82271146、82271147）
山东省重大科技创新项目(2022CXGC020506) （2022CXGC020506）
山东省博士后创新项目(SDCX-ZG-202400045) （SDCX-ZG-202400045）
