海南医学院学报2024，Vol.30Issue(23)：1827-1832,6.DOI:10.13210/j.cnki.jhmu.20240827.001
Hedgehog信号通路与缺血性脑卒中相关性的研究进展
Research progress on the correlation between Hedgehog signaling pathway and ischemic stroke
摘要
Abstract
Ischemic stroke is a common and serious cerebrovascular disease.The Hedgehog signaling pathway is a classic sig-naling pathway that controls embryonic development and plays a key role in the growth and proliferation of cells during embryonic development and formation.This pathway plays an important role in the occurrence and development of ischemic stroke by regulat-ing important pathological and physiological processes such as neuroinflammation,blood-brain barrier,angiogenesis,neuronal and synaptic regeneration.This article provides an overview of the Hedgehog signaling pathway and its role in ischemic stroke,in order to provide new theoretical basis for subsequent drug development.关键词
缺血性脑卒中/Hedgehog/Ptch/Smo/GliaKey words
Ischemic stroke/Hedgehog/Ptch/Smo/Glia分类
医药卫生引用本文复制引用
王亚敏,吕转,高静,冯晓东..Hedgehog信号通路与缺血性脑卒中相关性的研究进展[J].海南医学院学报,2024,30(23):1827-1832,6.基金项目
This study was supported by the National Natural Science Foundation of China(82174473,U2004131),and Science and Technology Research and Development Joint Fund of Henan Province(222301420064) 国家自然科学基金资助项目(82174473,U2004131) （82174473,U2004131）
河南省科技研发计划联合基金(222301420064) （222301420064）
