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壳聚糖基静电纺丝纳米纤维的制备及在组织工程中的应用

王韫沛 刘晨光

海洋科学2024,Vol.48Issue(10):62-75,14.
海洋科学2024,Vol.48Issue(10):62-75,14.DOI:10.11759/hykx20211031002

壳聚糖基静电纺丝纳米纤维的制备及在组织工程中的应用

Preparation of chitosan-based electrospinning nanofibers and their application in tissue engineering

王韫沛 1刘晨光1

作者信息

  • 1. 中国海洋大学 海洋生命学院,山东 青岛 266003
  • 折叠

摘要

Abstract

Electrospinning is a simple and efficient technology used to prepare continuous nano or microfibers.Chitosan is the only natural alkaline cationic polysaccharide.Chitosan-based nanofibers prepared through electro-spinning have the advantages of large specific surface area,high porosity,strong drug delivery ability,good bio-compatibility,good biodegradability,hemostasis,antibacterial ability,and healing promotion ability.Hence,they have broad application prospects in the field of tissue engineering.The preparation of chitosan-based electrospin-ning nanofibers and research advances of such nanofibers in bone,skin,blood vessels,and nerve tissue engineering have been reviewed.Finally,we present the future development direction of chitosan-based electrospinning nano-fibers in tissue engineering and expect to provide a theoretical reference for future research.

关键词

壳聚糖/静电纺丝/纳米纤维/组织工程

Key words

chitosan/electrospinning/nanofibers/tissue engineering

分类

化学化工

引用本文复制引用

王韫沛,刘晨光..壳聚糖基静电纺丝纳米纤维的制备及在组织工程中的应用[J].海洋科学,2024,48(10):62-75,14.

基金项目

国家重点研发计划-基于壳聚糖的大创伤急救修复医用材料研究开发(2018YFC0311102)[National Key R&D Program of China-Research and Devel-opment of Medical Materials for Emergency Repair of Severe Trauma Based on Chitosan,No.2018YFC0311102] (2018YFC0311102)

海洋科学

OA北大核心CSTPCD

1000-3096

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