实用临床医药杂志2024，Vol.28Issue(22)：16-20,5.DOI:10.7619/jcmp.20242036
喉罩麻醉与气管插管麻醉在低龄先天性心脏病患儿介入封堵术中的应用比较
Comparison of laryngeal mask airway anesthesia and endotracheal intubation anesthesia in interventional occlusion for young-age patients with congenital heart disease
摘要
Abstract
Objective To compare the application effects of laryngeal mask airway anesthesia and endotracheal intubation anesthesia in interventional occlusion for young-age patients with congeni-tal heart disease.Methods A total of 102 young-age patients with congenital heart disease undergo-ing interventional occlusion were enrolled and randomly divided into control group and observation group using a random number table method,with 51 patients in each group.The control group re-ceived endotracheal intubation anesthesia,while the observation group received sevoflurane anesthesia via laryngeal mask airway.The awakening time,extubation time,incidence of laryngeal spasm,and incidence of lung infection were compared between the two groups.Additionally,hemodynamic pa-rameters[heart rate(HR),mean arterial pressure(MAP)],oxidative stress indicators[malondial-dehyde(MDA),superoxide dismutase(SOD)],and myocardial injury indicators[creatine kinase-MB(CK-MB),heart-type fatty acid-binding protein(H-FABP)]levels at different time points were compared.Results The observation group had shorter awakening time and extubation time,and low-er incidence of lung infection and laryngeal spasm compared with the control group(P＜0.05).Before anesthesia(T0),there were no statistically significant differences in HR,MAP,MDA,SOD,CK-MB,and H-FABP levels between the two groups(P＞0.05).During laryngeal mask insertion or intuba-tion(T1),during arteriovenous puncture(T2),and immediately after occluder placement(T3),the observation group had lower HR,MAP,CK-MB,and H-FABP levels compared with the control group(P＜0.05).At T1,T2,and T3,the MDA levels in both groups were higher than that at T0,and the SOD levels were lower than that at T0;however,the observation group had lower MDA lev-els and higher SOD levels compared with the control group(P＜0.05).Conclusion Compared with endotracheal intubation anesthesia,sevoflurane anesthesia via laryngeal mask airway has a bet-ter application effect in interventional occlusion for young-age patients with congenital heart disease,thereby effectively maintaining intraoperative hemodynamic stability,shortening awakening time and extubation time,and exhibiting higher safety.关键词
喉罩/气管插管/先天性心脏病/低龄患儿/介入封堵术/血流动力学/肺部感染/喉痉挛Key words
laryngeal mask/endotracheal intubation/congenital heart disease/young-age children/interventional occlusion/hemodynamics/lung infection/laryngeal spasm分类
医药卫生引用本文复制引用
戴丹,刘婷婷,高静,胡瑶琴..喉罩麻醉与气管插管麻醉在低龄先天性心脏病患儿介入封堵术中的应用比较[J].实用临床医药杂志,2024,28(22):16-20,5.基金项目
国家自然科学基金项目(81901937) （81901937）
