解放军医学院学报2024，Vol.45Issue(9)：1006-1010,封3,6.DOI:10.12435/j.issn.2095-5227.2024.065
cGAS-STING在糖尿病及其并发症中的研究进展
Research advances in cGAS-STING in diabetes and its related complications
摘要
Abstract
The cGAS-STING signaling pathway is a critical pathway in the innate immune system.It can trigger the expression of a series of inflammatory factors,including type I interferon.The release of inflammatory factors can impair beta cell function and insulin resistance,leading to changes in insulin secretion and contributing to the development of diabetes and its complications.This article reviews the structure and mechanism of the cGAS-STING signaling pathway,as well as the research progress of cGAS-STING in diabetes and its related complications,aiming to provide new insights into the prevention and treatment of diabetes and its complications.关键词
cGAS-STING信号通路/糖尿病/糖尿病并发症/线粒体障碍/炎症Key words
cGAS-STING pathway/diabetes mellitus/diabetes complications/mitochondrial disorder/inflammation分类
医药卫生引用本文复制引用
孙敏,吴冰..cGAS-STING在糖尿病及其并发症中的研究进展[J].解放军医学院学报,2024,45(9):1006-1010,封3,6.基金项目
甘肃省卫生健康行业科研计划项目(GSWSKY2020-13) （GSWSKY2020-13）
