山东科学2024，Vol.37Issue(6)：31-41,11.DOI:10.3976/j.issn.1002-4026.20240044
基于多糖及熵权-TOPSIS的灵芝药材质量评价研究
Quality evaluation of Ganoderma lucidum as a medicinal material based on polysaccharides and entropy-weighted TOPSIS
摘要
Abstract
A comprehensive quantitative model that evaluates Ganoderma lucidum as a medicinal material was established based on polysaccharides and entropy-weighted technique for order preference by similarity to ideal solution(TOPSIS)to provide a reference for the quality evaluation of G.lucidum as a medicinal material and selecting the best batches.Initially,the yield,sugar composition,total sugar content,protein content,and uronic acid content of crude polysaccharides were determined formultiple batches of G.lucidum medicinal materials from the same origin.Subsequently,the data were nondimensionalized.Finally,entropy-weighted TOPSIS was used to comprehensively evaluate the quality of G.lucidum polysaccharides from different batches to establish the optimal standard.The yield,component content detection,and cluster heat map analysis of the polysaccharides showed that the polysaccharide yield and the total sugar and uronic acid content of G.lucidum medicinal materials from different batches varied significantly,whereas differences in the sugar composition and protein content were relatively minor.Polysaccharide yield and intrinsic indicators of the G.lucidum medicinal materials were not related to their origin.Entropy weight analysis showed that the polysaccharide yield weight coefficient was the largest at 23.68%,followed by total sugar at 21.35%and uronic acid content at 13.24%.The TOPSIS ranking and grouping results showed that cultivated G.lucidum fruiting bodies and red G.lucidum polysaccharides had better comprehensive scores.The quality of G.lucidum medicinal materials differ widely among different batches from the same origin.Entropy-weighted TOPSIS based on multi-index comprehensive evaluation achieved rapid,efficient,and accurate optimization of the source for G.lucidum polysaccharide extractasa medicinal material and has broad application prospects in production and comprehensive quality evaluation.This study provides a reference for the quality evaluation of other Chinese medicinal and decoction materials.关键词
灵芝/熵权-逼近理想解排序法/聚类分析/质量评价/粗多糖得率/糖组成/糖醛酸Key words
Ganoderma lucidum/entropy-weighted TOPSIS/cluster analysis/quality evaluation/crude polysaccharide yield/polysaccharide composition/uronic acid分类
中医学引用本文复制引用
杨志城,孙彩虹,叶冠..基于多糖及熵权-TOPSIS的灵芝药材质量评价研究[J].山东科学,2024,37(6):31-41,11.基金项目
上海医药中药传承和创新平台能力建设(2020006) （2020006）
