食管疾病2024，Vol.6Issue(4)：241-245,5.DOI:10.15926/j.cnki.issn2096-7381.2024.04.001
食管鳞状细胞癌化疗联合免疫治疗后病理消退模式分析
The Pathological Regression Pattern of Residual Tumor in Radical Specimens of Patients with Esophageal Squamous Cell Carcinoma after Preoperative Chemotherapy Combined with Immunotherapy
奚丽娜 1李军扩 1孙媛媛 1杨海军1
作者信息
- 1. 安阳市肿瘤医院,河南 安阳,455000
- 折叠
摘要
Abstract
Objective To explore the pathological regression pattern of residual tumor in radical specimens of patients with locally advanced esophageal squamous cell carcinoma after preoperative chemotherapy combined with immunotherapy.Methods A retrospective analysis was performed on the specimens of 411 patients who underwent radical resection of esophageal cancer after 2-4 cycles of chemotherapy combined with immunotherapy.The specimens were classified and analyzed according to the regression direction of the residual tumor in the esophageal wall.Results Among the 411cases,70 cases(17.03%)were regressed into the lumen,14 cases(3.41%)were regressed into the fibrous membrane,7 cases(1.70%)were concentric regressed,199 cases(48.42%)were random regressed,and 120 cases(29.20%)were completely regressed.One case was not yet classified.Conclusion Random regression was the most common direction of residual tumor regression,followed by complete regression,concentric regressed was the least.The cases of complete regression provide new data support for the esophageal preservation treatment strategy for patients with esophageal cancer.关键词
食管鳞状细胞癌/免疫治疗/化疗/残留肿瘤/消退模式Key words
esophageal squamous cell carcinoma/immunotherapy/chemotherapy/residual tumor,regression pattern分类
医药卫生引用本文复制引用
奚丽娜,李军扩,孙媛媛,杨海军..食管鳞状细胞癌化疗联合免疫治疗后病理消退模式分析[J].食管疾病,2024,6(4):241-245,5.
