食管疾病2024，Vol.6Issue(4)：315-320,6.DOI:10.15926/j.cnki.issn2096-7381.2024.04.015
纳米载药系统在食管癌放疗增敏联合多途径治疗中的应用
Application of Nano-drug-loading System in Combination with Multi-pathway Radiotherapy for Esophageal Carcinoma
摘要
Abstract
Esophageal carcinoma is a typical malignant tumor.Its treatment usually includes surgery,chemotherapy and radiotherapy.In recent years,many innovative methods have emerged in the field of radio-therapy,which can enhance the sensitivity of cancer cells to radiation through drugs or other methods,while reducing the damage to the surrounding normal tissues,so as to improve the effect of radiotherapy for esopha-geal carcinoma.As a new drug delivery platform,nano-drug delivery system has the characteristics of size effect and high specific surface area,especially can achieve targeted drug release in vivo.Nano-drug delivery system shows great potential in enhancing the sensitivity of radiotherapy for esophageal cancer by changing the drug distribution in vivo,reducing toxicity and increasing orientation.This paper reviews the research progress of nano-drug delivery system in radiosensitization of esophageal carcinoma.The potential and advan-tages of the combination of radiosensitization and other therapeutic methods are discussed from several key as-pects of the current research on nano-drug delivery system.关键词
食管癌/放疗增敏/靶向治疗/纳米载药系统Key words
esophageal cancer/radiation therapy sensitization/targeted therapy/nanoparticles drug deliv-ery system分类
医药卫生引用本文复制引用
臧珂妍,赵亚莉,杨平娟,张伟,喻莹,李佳怡,石林林,高社干..纳米载药系统在食管癌放疗增敏联合多途径治疗中的应用[J].食管疾病,2024,6(4):315-320,6.基金项目
河南省中原英才计划(育才系列)河南省医学科技攻关省部共建重点项目(SBGJ202102199)洛阳市社会发展公益专项医疗卫生重点项目(2302016A) （育才系列）
