药用真菌桑黄中多酚类成分药用机理研究进展OA北大核心CSTPCD

Sanghuang,a type of xylobasidiomycetes belonging to the Rustachromataceae family,is highly regarded as a valuable perennial medicinal fungus.Due to its strong biological activity,it has attracted extensive attention and research enthusiasm from scholars in various fields worldwide.Modern pharmacology has found that Sanghuang has extremely high medicinal value due to its rich content of biologically active substances,particularly polyphenols are one of the most important active ingredients.These polyphenols provide Sanghuang with significant pharmacological activities such as anti-tumor effects,antioxidant properties,anti-aging effects,blood sugar reduction capabilities,immune enhancement abilities and damage repair functions.In this paper,we sort the development process of Sanghuang species and briefly summarize their main distribution areas.We also compile and summarize the isolated polyphenols from Sanghuang fungi along with their biological activities.Based on current research on the biological activities of Sanghuang fungi,we systematically summarize the progress in studying the medicinal effects of major polyphenols and provide detailed insights into their potential mechanisms for antioxidant properties,anti-inflammatory effects,anti-tumor capabilities as well as adjuvant treatment for diabetic complications.Additionally,we discuss key issues existing in polyphenol studies related to Sanghuang fungi while addressing current developmental bottlenecks faced by Sanghuang industry.Furthermore,we propose future research directions for polyphenols derived from Sanghaung fungi,which lay a theoretical foundation for improving therapeutic efficacy and rational application of these compounds as drugs.This provides new ideas for applying polyphenols in medicine.