生物技术通报2024，Vol.40Issue(11)：3-13,11.DOI:10.13560/j.cnki.biotech.bull.1985.2024-0668
药用真菌桑黄中多酚类成分药用机理研究进展
Progress on the Medicinal Mechanism of Polyphenols in the Medicinal Fungus Sanghuang
摘要
Abstract
Sanghuang,a type of xylobasidiomycetes belonging to the Rustachromataceae family,is highly regarded as a valuable perennial medicinal fungus.Due to its strong biological activity,it has attracted extensive attention and research enthusiasm from scholars in various fields worldwide.Modern pharmacology has found that Sanghuang has extremely high medicinal value due to its rich content of biologically active substances,particularly polyphenols are one of the most important active ingredients.These polyphenols provide Sanghuang with significant pharmacological activities such as anti-tumor effects,antioxidant properties,anti-aging effects,blood sugar reduction capabilities,immune enhancement abilities and damage repair functions.In this paper,we sort the development process of Sanghuang species and briefly summarize their main distribution areas.We also compile and summarize the isolated polyphenols from Sanghuang fungi along with their biological activities.Based on current research on the biological activities of Sanghuang fungi,we systematically summarize the progress in studying the medicinal effects of major polyphenols and provide detailed insights into their potential mechanisms for antioxidant properties,anti-inflammatory effects,anti-tumor capabilities as well as adjuvant treatment for diabetic complications.Additionally,we discuss key issues existing in polyphenol studies related to Sanghuang fungi while addressing current developmental bottlenecks faced by Sanghuang industry.Furthermore,we propose future research directions for polyphenols derived from Sanghaung fungi,which lay a theoretical foundation for improving therapeutic efficacy and rational application of these compounds as drugs.This provides new ideas for applying polyphenols in medicine.关键词
药用真菌桑黄/多酚类物质/生物活性/药用机理Key words
medicinal fungus Sanghuang/polyphenols/biological activity/medicinal mechanism引用本文复制引用
赵睿萌,王梦雨,吕国英,宋婷婷,张作法..药用真菌桑黄中多酚类成分药用机理研究进展[J].生物技术通报,2024,40(11):3-13,11.基金项目
浙江省农业新品种选育重大科技专项(2021C02073-7),海宁市科技计划农业项目(2022029) （2021C02073-7）
