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黑虎掌菌的化学成分及其药理作用研究进展OA北大核心CSTPCD

Research Progress in the Chemical Components and Pharmacological Effects of Sarcodon imbricatus

中文摘要英文摘要

黑虎掌菌(Sarcodon imbricatus)又名枣翘鳞肉齿菌,肉质细嫩、味道鲜美,是著名的食药两用菌之一,其分布广泛,受国内外众多学者关注.黑虎掌菌子实体和菌丝体中富含有多糖类物质、蛋白质、矿物质、氨基酸、微量元素、甾醇类等营养物质,具有抗肿瘤、抗氧化以及抑菌等药理活性,应用前景广阔.随着黑虎掌菌多糖成分的分离纯化与鉴定,以及药理活性的相关研究,黑虎掌菌多糖的提取工艺和功效分析机制愈发明朗,但是多糖成分在体内如何调控蛋白质和基因等的表达,以及黑虎掌菌其他成分功效和机制的研究,仍需进一步探索.本文梳理并总结了已报道的黑虎掌菌研究现状,介绍了子实体的形态特征、归纳总结子实体和菌丝体的化学成分,讨论了菌丝体的发酵条件、不同提取方法下子实体的多糖和多肽得率,并概述黑虎掌菌在抗肿瘤、抗氧化和抑菌方面的研究进展.最后,对黑虎掌菌的研究与开发前景进行展望,旨在为相关蘑菇产业研究提供理论依据和为开发利用提供借鉴.

Sarcodon imbricatus,also known as Tremellodon gelatinosum,tasted tender and delicious,is one of the famous edible and medicinal dual-use fungi,widely distributed and has attracted the attention of many scholars at home and abroad.Its fruiting body and mycelium are rich in nutrients such as polysaccharides,proteins,minerals,amino acids,trace elements,sterols,etc.,which have pharmacological activities such as anti-tumor,antioxidant,and antibacterial effects,and thus have broad application prospects.With the isolation,purification,and identification of polysaccharides from S.imbricatus,as well as related studies on pharmacological activity,the extraction process and efficacy analysis mechanism of polysaccharides from S.imbricatus have become increasingly clear.However,further exploration is needed on how polysaccharides regulate the expressions of proteins and genes in vivo,as well as the efficacy and mechanisms of other components in S.imbricatus.This article sorts and summarizes the reported status of studies on S.imbricatus.Firstly,we summarized the morphological characteristics of the fruiting body,and the chemical compositions of the fruiting body and mycelium.Secondly,we discussed the fermentation conditions of mycelium and the yield of polysaccharides and peptides from fruiting body using different extraction methods.Then,we summarized the research progresses of using S.imbricatus in anti-tumor,antioxidant,and antibacterial aspects.Finally,we discussed the research and development prospects of S.imbricatus,aiming to provide theoretical basis for related mushroom industry research and reference for development and utilization.

李臣亮;蔡雪莹;杨安慧

吉林大学生命科学学院,长春 130012吉林大学生命科学学院,长春 130012||中国科学院天津工业生物技术研究所,天津 300000吉林大学生命科学学院,长春 130012

黑虎掌菌化学成分液体发酵提取方法药理活性

Sarcodon imbricatuschemical compositionliquid fermentationextraction methodpharmacological activity

《生物技术通报》 2024 (11)

24-33,10

10.13560/j.cnki.biotech.bull.1985.2024-0476

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