生物技术通报2024，Vol.40Issue(11)：113-124,12.DOI:10.13560/j.cnki.biotech.bull.1985.2024-0298
昆虫相关放线菌资源挖掘利用研究进展
Progress in the Mining and Utilization of Insect-associated Actinomycete Resources
摘要
Abstract
Insects are one of the most species-diverse groups of organisms in nature,and they have established close symbiotic relationships with a variety of functionally unique symbionts during their long evolutionary process.These symbiotic relationships were understood to be mutually beneficial in the early days,and recent studies have also revealed commensalism and parasitism.Among these symbionts,actinomycetes are a special group of microorganisms that can be found in the insect gut,feces,antennae,exoskeleton,and the fungus gardens of fungus-growing insects,which help host insects to defend themselves against pathogens,parasites,and predators,and they play an important role in maintaining the survival and reproduction of host insects.In recent years,a variety of novel compounds have been isolated from the metabolites produced by insect-associated actinomycetes,which can inhibit the proliferation of various plant and animal pathogens,tumor cells,and cancer cells.Therefore,the study on insect-associated actinomycetes can not only analyze the symbiotic mechanism between host and microorganisms but also provide new options for developing biopesticides and biopharmaceuticals.This paper reviews the research progress on the mining and utilization of insect-associated actinomycetes,mainly summarizes the resources and functional diversity of different species of insect-associated actinomycetes,concurrently classifies the secondary metabolites of insect-associated actinomycetes with important activities according to the structural differences,including polypeptide,quinine and polyketide,lactone,alkaloid and other compounds,as well as explores the functional diversity of these secondary metabolites,thus providing a foundation for understanding the operation of ecosystems,discovering new bioactive substances,and developing new biopesticides and pharmaceuticals.关键词
昆虫/放线菌/次级代谢产物Key words
insects/actinomycetes/secondary metabolites引用本文复制引用
赵正阳,谢丙炎,成新跃,李惠霞..昆虫相关放线菌资源挖掘利用研究进展[J].生物技术通报,2024,40(11):113-124,12.基金项目
国家自然科学基金项目(32260654),国家重点研发计划项目(2023YFD1400400) （32260654）
